Pigment Cells of the Eyes in People with Vitiligo

Aaron B. Lerner, James J. Nordlund, Daniel M. Albert

Research output: Contribution to journalLetter

19 Scopus citations

Abstract

To the Editor: White patches of skin and gray hair occur in people with vitiligo because the pigment cells, melanocytes, are destroyed in skin and hair follicles. A combination of immunologic and cytotoxic mechanisms produces this loss of melanocytes. The prevalence of vitiligo is high in patients with disorders of autoimmunity such as hyperthyroidism, thyroiditis, adrenal insufficiency and pernicious anemia. In addition, patients with melanomas who have strong immunity against malignant melanocytes frequently have vitiligo. One fascinating aspect about the subject is that no matter how extensive the pigment loss and how great the duration of loss, the color. . .

Original languageEnglish (US)
Number of pages1
JournalNew England Journal of Medicine
Volume296
Issue number4
DOIs
StatePublished - Jan 27 1977

ASJC Scopus subject areas

  • Medicine(all)

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