Physiology of the Fetal and Neonatal Circulations and Fetal Cardiac Surgery

Ashok Muralidaran, Vadiyala Mohan Reddy, Frank L. Hanley

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter covers the physiology of the fetal and neonatal circulations and fetal cardiac surgery. The major flow patterns, cardiac output, oxygenation, and distribution are covered in detail, including intracardiac and vascular pressures. At birth, the pattern of circulation changes from the fetal "parallel" type to the adult "series" type; these changes are discussed. The second part of the chapter covers fetal cardiac surgery. Animal models are discussed with reference to hemodynamics and the fetal stress response. Finally, the role of the endothelium in placental dysfunction, the fetal bypass circuit, and fetal myocardial protection are covered.

Original languageEnglish (US)
Title of host publicationPediatric Cardiac Surgery
Subtitle of host publicationFourth Edition
PublisherBlackwell Publishing Ltd
Number of pages8
ISBN (Print)9781405196529
StatePublished - Feb 28 2013
Externally publishedYes


  • Combined ventricular output
  • Fetal bypass circuit
  • Fetal cardiac surgery
  • Fetal circulation
  • Fetal myocardial protection
  • Fetal surgery
  • Pediatric
  • Placental dysfunction

ASJC Scopus subject areas

  • Medicine(all)


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