Physiological and functional consequences of caregiving for relatives with dementia

Irina Fonareva, Barry Oken

Research output: Contribution to journalArticle

69 Citations (Scopus)

Abstract

Background: Chronic stress negatively affects health and well-being. A growing population of informal dementia caregivers experience chronic stress associated with extraordinary demands of caring for a relative with dementia. This review summarizes physiological and functional changes due to chronic dementia caregiver stress. Methods: A literature search for papers assessing effects of dementia caregiving was conducted focusing on publications evaluating differences between caregivers and non-caregivers in objective measures of health and cognition. Results: The review identified 37 studies describing data from 4,145 participants including 749 dementia caregivers and 3,396 non-caregiver peers. Objective outcome measures affected in dementia caregivers included markers of dyscoagulation, inflammation, and cell aging as well as measures of immune function, sleep, and cognition. Though diverse in designs, samples, and study quality, the majority of the studies indicated increased vulnerability of dementia caregivers to detrimental changes in health and cognition. Demographic and personality characteristics moderating or mediating effects of chronic stress in caregivers were also reviewed. Conclusions: There is accumulating evidence that chronic dementia caregiver stress increases their vulnerability to disease and diminishes their ability to provide optimal care. Clinicians and society need to appreciate the extent of deleterious effects of chronic stress on dementia caregiver health.

Original languageEnglish (US)
Pages (from-to)725-747
Number of pages23
JournalInternational Psychogeriatrics
Volume26
Issue number5
DOIs
StatePublished - 2014

Fingerprint

Caregivers
Dementia
Cognition
Health
Aptitude
Cell Aging
Personality
Publications
Sleep
Demography
Outcome Assessment (Health Care)
Inflammation
Population

Keywords

  • cognition
  • dementia caregivers
  • health
  • physiological marker
  • sleep quality

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Gerontology
  • Clinical Psychology
  • Medicine(all)

Cite this

Physiological and functional consequences of caregiving for relatives with dementia. / Fonareva, Irina; Oken, Barry.

In: International Psychogeriatrics, Vol. 26, No. 5, 2014, p. 725-747.

Research output: Contribution to journalArticle

@article{223f04ec379c44a1a91e3dd9d723447e,
title = "Physiological and functional consequences of caregiving for relatives with dementia",
abstract = "Background: Chronic stress negatively affects health and well-being. A growing population of informal dementia caregivers experience chronic stress associated with extraordinary demands of caring for a relative with dementia. This review summarizes physiological and functional changes due to chronic dementia caregiver stress. Methods: A literature search for papers assessing effects of dementia caregiving was conducted focusing on publications evaluating differences between caregivers and non-caregivers in objective measures of health and cognition. Results: The review identified 37 studies describing data from 4,145 participants including 749 dementia caregivers and 3,396 non-caregiver peers. Objective outcome measures affected in dementia caregivers included markers of dyscoagulation, inflammation, and cell aging as well as measures of immune function, sleep, and cognition. Though diverse in designs, samples, and study quality, the majority of the studies indicated increased vulnerability of dementia caregivers to detrimental changes in health and cognition. Demographic and personality characteristics moderating or mediating effects of chronic stress in caregivers were also reviewed. Conclusions: There is accumulating evidence that chronic dementia caregiver stress increases their vulnerability to disease and diminishes their ability to provide optimal care. Clinicians and society need to appreciate the extent of deleterious effects of chronic stress on dementia caregiver health.",
keywords = "cognition, dementia caregivers, health, physiological marker, sleep quality",
author = "Irina Fonareva and Barry Oken",
year = "2014",
doi = "10.1017/S1041610214000039",
language = "English (US)",
volume = "26",
pages = "725--747",
journal = "International Psychogeriatrics",
issn = "1041-6102",
publisher = "Cambridge University Press",
number = "5",

}

TY - JOUR

T1 - Physiological and functional consequences of caregiving for relatives with dementia

AU - Fonareva, Irina

AU - Oken, Barry

PY - 2014

Y1 - 2014

N2 - Background: Chronic stress negatively affects health and well-being. A growing population of informal dementia caregivers experience chronic stress associated with extraordinary demands of caring for a relative with dementia. This review summarizes physiological and functional changes due to chronic dementia caregiver stress. Methods: A literature search for papers assessing effects of dementia caregiving was conducted focusing on publications evaluating differences between caregivers and non-caregivers in objective measures of health and cognition. Results: The review identified 37 studies describing data from 4,145 participants including 749 dementia caregivers and 3,396 non-caregiver peers. Objective outcome measures affected in dementia caregivers included markers of dyscoagulation, inflammation, and cell aging as well as measures of immune function, sleep, and cognition. Though diverse in designs, samples, and study quality, the majority of the studies indicated increased vulnerability of dementia caregivers to detrimental changes in health and cognition. Demographic and personality characteristics moderating or mediating effects of chronic stress in caregivers were also reviewed. Conclusions: There is accumulating evidence that chronic dementia caregiver stress increases their vulnerability to disease and diminishes their ability to provide optimal care. Clinicians and society need to appreciate the extent of deleterious effects of chronic stress on dementia caregiver health.

AB - Background: Chronic stress negatively affects health and well-being. A growing population of informal dementia caregivers experience chronic stress associated with extraordinary demands of caring for a relative with dementia. This review summarizes physiological and functional changes due to chronic dementia caregiver stress. Methods: A literature search for papers assessing effects of dementia caregiving was conducted focusing on publications evaluating differences between caregivers and non-caregivers in objective measures of health and cognition. Results: The review identified 37 studies describing data from 4,145 participants including 749 dementia caregivers and 3,396 non-caregiver peers. Objective outcome measures affected in dementia caregivers included markers of dyscoagulation, inflammation, and cell aging as well as measures of immune function, sleep, and cognition. Though diverse in designs, samples, and study quality, the majority of the studies indicated increased vulnerability of dementia caregivers to detrimental changes in health and cognition. Demographic and personality characteristics moderating or mediating effects of chronic stress in caregivers were also reviewed. Conclusions: There is accumulating evidence that chronic dementia caregiver stress increases their vulnerability to disease and diminishes their ability to provide optimal care. Clinicians and society need to appreciate the extent of deleterious effects of chronic stress on dementia caregiver health.

KW - cognition

KW - dementia caregivers

KW - health

KW - physiological marker

KW - sleep quality

UR - http://www.scopus.com/inward/record.url?scp=84897574564&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897574564&partnerID=8YFLogxK

U2 - 10.1017/S1041610214000039

DO - 10.1017/S1041610214000039

M3 - Article

C2 - 24507463

AN - SCOPUS:84897574564

VL - 26

SP - 725

EP - 747

JO - International Psychogeriatrics

JF - International Psychogeriatrics

SN - 1041-6102

IS - 5

ER -