Photoimmunology-illuminating the immune system through photobiology

Justin Leitenberger, Heidi T. Jacobe, Ponciano D. Cruz

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

We review the field of photoimmunology with emphasis on immunosuppression induced by ultraviolet B radiation. Recent studies have focused on UVB-induced alterations in epidermal Langerhans cell function, resulting in a shift from Th1 to Th2 phenotype and the activation of regulatory T cells as the source of IL-10 that is central to this form of immunosuppression.

Original languageEnglish (US)
Pages (from-to)65-70
Number of pages6
JournalSeminars in Immunopathology
Volume29
Issue number1
DOIs
StatePublished - Apr 2007
Externally publishedYes

Keywords

  • Antigen-presenting cells
  • Cytokines
  • Immunosuppression
  • Regulatory T cells
  • Ultraviolet radiation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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