Phase-Dependent Effects of Closed-Loop Tactile Feedback on Gait Stability in Parkinson's Disease

Peter C. Fino, Martina Mancini

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Gait disturbances in people with Parkinson's disease (PD) are a major cause for functional dependence and have recently been shown to be the largest risk factor for falls, institutionalization and death in PD. The use of external cues has been successful at improving gait in people with PD, but the effect of external cues on gait stability is unclear. We examined whether different forms of cueing, open-loop and closed-loop, influenced the local dynamic stability of three critical phases of gait. Forty-three adults with PD completed six, two-minute long walking trials in the following cued conditions: no cue (B), open-loop cueing, fixed auditory cue (OL), closed-loop cueing, tactile feedback delivered to wrist when the ipsilateral foot contacted with the ground (CL). Conditions were performed with and without a cognitive task. Kinematic data were recorded with inertial sensors. Only CL cueing was associated with changes in trunk stability, and these changes were only evident during the weight transfer phase of gait. Both OL and CL caused reductions in overall gait speed, stride length, and an increase in stride time. While CL cueing significantly influenced local dynamic stability during weight transfer, it remains unknown whether these changes are associated with more or less global stability. Future research will explore the clinical implications.

Original languageEnglish (US)
Article number9099479
Pages (from-to)1636-1641
Number of pages6
JournalIEEE Transactions on Neural Systems and Rehabilitation Engineering
Volume28
Issue number7
DOIs
StatePublished - Jul 2020

Keywords

  • Cueing
  • Lyapunov exponents
  • Parkinson's disease
  • accelerometers
  • dual-task
  • gait stability
  • wearable sensors

ASJC Scopus subject areas

  • Internal Medicine
  • Neuroscience(all)
  • Biomedical Engineering
  • Rehabilitation

Fingerprint

Dive into the research topics of 'Phase-Dependent Effects of Closed-Loop Tactile Feedback on Gait Stability in Parkinson's Disease'. Together they form a unique fingerprint.

Cite this