Peripheral arterial disease is associated with higher rates of hip bone loss and increased fracture risk in older men

Tracie C. Collins, Susan K. Ewing, Susan J. Diem, Brent C. Taylor, Eric Orwoll, Steven R. Cummings, Elsa S. Strotmeyer, Kristine E. Ensrud

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

BACKGROUND-: Peripheral arterial disease (PAD) and osteoporosis are chronic illnesses that increase in prevalence with aging and certain metabolic disorders. The association between PAD, rates of bone loss, and fracture risk in older men is uncertain. METHODS AND RESULTS-: We sought to test the hypothesis that PAD is associated with higher rates of bone loss and increased fracture risk. We analyzed data from a prospective cohort study involving 6 US centers and 5781 men at least 65 years of age. We assessed ankle-brachial index and hip bone mineral density, followed up prospectively for changes in hip bone mineral density and fractures. PAD was defined as a baseline ankle-brachial index

Original languageEnglish (US)
Pages (from-to)2305-2312
Number of pages8
JournalCirculation
Volume119
Issue number17
DOIs
StatePublished - May 5 2009

Fingerprint

Pelvic Bones
Peripheral Arterial Disease
Ankle Brachial Index
Bone Fractures
Bone Density
Arm Bones
Osteoporosis
Chronic Disease
Cohort Studies
Prospective Studies
Bone and Bones

Keywords

  • Bone loss
  • Fractures
  • Peripheral arterial disease

ASJC Scopus subject areas

  • Physiology (medical)
  • Cardiology and Cardiovascular Medicine

Cite this

Peripheral arterial disease is associated with higher rates of hip bone loss and increased fracture risk in older men. / Collins, Tracie C.; Ewing, Susan K.; Diem, Susan J.; Taylor, Brent C.; Orwoll, Eric; Cummings, Steven R.; Strotmeyer, Elsa S.; Ensrud, Kristine E.

In: Circulation, Vol. 119, No. 17, 05.05.2009, p. 2305-2312.

Research output: Contribution to journalArticle

Collins, TC, Ewing, SK, Diem, SJ, Taylor, BC, Orwoll, E, Cummings, SR, Strotmeyer, ES & Ensrud, KE 2009, 'Peripheral arterial disease is associated with higher rates of hip bone loss and increased fracture risk in older men', Circulation, vol. 119, no. 17, pp. 2305-2312. https://doi.org/10.1161/CIRCULATIONAHA.108.820993
Collins, Tracie C. ; Ewing, Susan K. ; Diem, Susan J. ; Taylor, Brent C. ; Orwoll, Eric ; Cummings, Steven R. ; Strotmeyer, Elsa S. ; Ensrud, Kristine E. / Peripheral arterial disease is associated with higher rates of hip bone loss and increased fracture risk in older men. In: Circulation. 2009 ; Vol. 119, No. 17. pp. 2305-2312.
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AU - Strotmeyer, Elsa S.

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