Pathway Commons, a web resource for biological pathway data

Ethan G. Cerami, Benjamin E. Gross, Emek Demir, Igor Rodchenkov, Özgün Babur, Nadia Anwar, Nikolaus Schultz, Gary D. Bader, Chris Sander

Research output: Contribution to journalArticle

621 Scopus citations

Abstract

Pathway Commons (http://www.pathwaycommons .org) is a collection of publicly available pathway data from multiple organisms. Pathway Commons provides a web-based interface that enables biologists to browse and search a comprehensive collection of pathways from multiple sources represented in a common language, a download site that provides integrated bulk sets of pathway information in standard or convenient formats and a web service that software developers can use to conveniently query and access all data. Database providers can share their pathway data via a common repository. Pathways include biochemical reactions, complex assembly, transport and catalysis events and physical interactions involving proteins, DNA, RNA, small molecules and complexes. Pathway Commons aims to collect and integrate all public pathway data available in standard formats. Pathway Commons currently contains data from nine databases with over 1400 pathways and 687 000 interactions and will be continually expanded and updated.

Original languageEnglish (US)
Pages (from-to)D685-D690
JournalNucleic acids research
Volume39
Issue numberSUPPL. 1
DOIs
StatePublished - Jan 2011

ASJC Scopus subject areas

  • Genetics

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    Cerami, E. G., Gross, B. E., Demir, E., Rodchenkov, I., Babur, Ö., Anwar, N., Schultz, N., Bader, G. D., & Sander, C. (2011). Pathway Commons, a web resource for biological pathway data. Nucleic acids research, 39(SUPPL. 1), D685-D690. https://doi.org/10.1093/nar/gkq1039