Patch-testing North American Lip Dermatitis patients: Data from the North American Contact Dermatitis Group, 2001 to 2004

Kathryn A. Zug, Rachel Kornik, Donald V. Belsito, Vincent A. DeLeo, Joseph F. Fowler, Howard I. Maibach, James G. Marks, C. G Toby Mathias, Melanie D. Pratt, Robert L. Rietschel, Denis Sasseville, Frances Storrs, James S. Taylor, Erin M. Warshaw

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Background: The most common differential diagnoses for patients presenting with lip dermatitis or inflammation include atopic, allergic, and irritant contact dermatitis. Patch testing can be performed to identify the allergic contact conditions. Objective: To report North American Contact Dermatitis Group (NACDG) patch-test results of patients who presented for patch testing with only lip involvement from 2001 to 2004. Patient characteristics, allergen frequencies, relevance, final diagnoses, and relevant allergic sources not in the NACDG screening series were evaluated. Methods: The NACDG 2001-2004 database was used to select patients presenting with only lip involvement. Results: Of 10,061 patients tested, 2% (n = 196) had lips as the sole involved site. Most (84.2%) were women. After patch testing, 38.3% (n = 75) were diagnosed with allergic contact cheilitis. Fragrance mix, Myroxilon pereirae, and nickel were the most common relevant allergens. Of 75 patients, 27 (36%) had relevant positive patch-test reactions to items not on the NACDG series; lipstick and cosmetics were the predominant sources. Conclusions: Patch testing is valuable in the evaluation and identification of contact allergy in patients referred for lip dermatitis. The use of supplementary allergens based on history and exposure is important in the identification of additional relevant allergens. Over a third of patients with contact allergy had other factors, such as irritant dermatitis, considered relevant to their condition.

Original languageEnglish (US)
Pages (from-to)202-208
Number of pages7
JournalDermatitis
Volume19
Issue number4
DOIs
StatePublished - Jul 2008
Externally publishedYes

Fingerprint

Contact Dermatitis
Dermatitis
Lip
Allergens
Irritant Dermatitis
Patch Tests
Hypersensitivity
Cheilitis
Allergic Contact Dermatitis
Nickel
Cosmetics
Differential Diagnosis
History
Databases
Inflammation

ASJC Scopus subject areas

  • Dermatology

Cite this

Zug, K. A., Kornik, R., Belsito, D. V., DeLeo, V. A., Fowler, J. F., Maibach, H. I., ... Warshaw, E. M. (2008). Patch-testing North American Lip Dermatitis patients: Data from the North American Contact Dermatitis Group, 2001 to 2004. Dermatitis, 19(4), 202-208. https://doi.org/10.2310/6620.2008.07046

Patch-testing North American Lip Dermatitis patients : Data from the North American Contact Dermatitis Group, 2001 to 2004. / Zug, Kathryn A.; Kornik, Rachel; Belsito, Donald V.; DeLeo, Vincent A.; Fowler, Joseph F.; Maibach, Howard I.; Marks, James G.; Mathias, C. G Toby; Pratt, Melanie D.; Rietschel, Robert L.; Sasseville, Denis; Storrs, Frances; Taylor, James S.; Warshaw, Erin M.

In: Dermatitis, Vol. 19, No. 4, 07.2008, p. 202-208.

Research output: Contribution to journalArticle

Zug, KA, Kornik, R, Belsito, DV, DeLeo, VA, Fowler, JF, Maibach, HI, Marks, JG, Mathias, CGT, Pratt, MD, Rietschel, RL, Sasseville, D, Storrs, F, Taylor, JS & Warshaw, EM 2008, 'Patch-testing North American Lip Dermatitis patients: Data from the North American Contact Dermatitis Group, 2001 to 2004', Dermatitis, vol. 19, no. 4, pp. 202-208. https://doi.org/10.2310/6620.2008.07046
Zug, Kathryn A. ; Kornik, Rachel ; Belsito, Donald V. ; DeLeo, Vincent A. ; Fowler, Joseph F. ; Maibach, Howard I. ; Marks, James G. ; Mathias, C. G Toby ; Pratt, Melanie D. ; Rietschel, Robert L. ; Sasseville, Denis ; Storrs, Frances ; Taylor, James S. ; Warshaw, Erin M. / Patch-testing North American Lip Dermatitis patients : Data from the North American Contact Dermatitis Group, 2001 to 2004. In: Dermatitis. 2008 ; Vol. 19, No. 4. pp. 202-208.
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abstract = "Background: The most common differential diagnoses for patients presenting with lip dermatitis or inflammation include atopic, allergic, and irritant contact dermatitis. Patch testing can be performed to identify the allergic contact conditions. Objective: To report North American Contact Dermatitis Group (NACDG) patch-test results of patients who presented for patch testing with only lip involvement from 2001 to 2004. Patient characteristics, allergen frequencies, relevance, final diagnoses, and relevant allergic sources not in the NACDG screening series were evaluated. Methods: The NACDG 2001-2004 database was used to select patients presenting with only lip involvement. Results: Of 10,061 patients tested, 2{\%} (n = 196) had lips as the sole involved site. Most (84.2{\%}) were women. After patch testing, 38.3{\%} (n = 75) were diagnosed with allergic contact cheilitis. Fragrance mix, Myroxilon pereirae, and nickel were the most common relevant allergens. Of 75 patients, 27 (36{\%}) had relevant positive patch-test reactions to items not on the NACDG series; lipstick and cosmetics were the predominant sources. Conclusions: Patch testing is valuable in the evaluation and identification of contact allergy in patients referred for lip dermatitis. The use of supplementary allergens based on history and exposure is important in the identification of additional relevant allergens. Over a third of patients with contact allergy had other factors, such as irritant dermatitis, considered relevant to their condition.",
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AU - Kornik, Rachel

AU - Belsito, Donald V.

AU - DeLeo, Vincent A.

AU - Fowler, Joseph F.

AU - Maibach, Howard I.

AU - Marks, James G.

AU - Mathias, C. G Toby

AU - Pratt, Melanie D.

AU - Rietschel, Robert L.

AU - Sasseville, Denis

AU - Storrs, Frances

AU - Taylor, James S.

AU - Warshaw, Erin M.

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N2 - Background: The most common differential diagnoses for patients presenting with lip dermatitis or inflammation include atopic, allergic, and irritant contact dermatitis. Patch testing can be performed to identify the allergic contact conditions. Objective: To report North American Contact Dermatitis Group (NACDG) patch-test results of patients who presented for patch testing with only lip involvement from 2001 to 2004. Patient characteristics, allergen frequencies, relevance, final diagnoses, and relevant allergic sources not in the NACDG screening series were evaluated. Methods: The NACDG 2001-2004 database was used to select patients presenting with only lip involvement. Results: Of 10,061 patients tested, 2% (n = 196) had lips as the sole involved site. Most (84.2%) were women. After patch testing, 38.3% (n = 75) were diagnosed with allergic contact cheilitis. Fragrance mix, Myroxilon pereirae, and nickel were the most common relevant allergens. Of 75 patients, 27 (36%) had relevant positive patch-test reactions to items not on the NACDG series; lipstick and cosmetics were the predominant sources. Conclusions: Patch testing is valuable in the evaluation and identification of contact allergy in patients referred for lip dermatitis. The use of supplementary allergens based on history and exposure is important in the identification of additional relevant allergens. Over a third of patients with contact allergy had other factors, such as irritant dermatitis, considered relevant to their condition.

AB - Background: The most common differential diagnoses for patients presenting with lip dermatitis or inflammation include atopic, allergic, and irritant contact dermatitis. Patch testing can be performed to identify the allergic contact conditions. Objective: To report North American Contact Dermatitis Group (NACDG) patch-test results of patients who presented for patch testing with only lip involvement from 2001 to 2004. Patient characteristics, allergen frequencies, relevance, final diagnoses, and relevant allergic sources not in the NACDG screening series were evaluated. Methods: The NACDG 2001-2004 database was used to select patients presenting with only lip involvement. Results: Of 10,061 patients tested, 2% (n = 196) had lips as the sole involved site. Most (84.2%) were women. After patch testing, 38.3% (n = 75) were diagnosed with allergic contact cheilitis. Fragrance mix, Myroxilon pereirae, and nickel were the most common relevant allergens. Of 75 patients, 27 (36%) had relevant positive patch-test reactions to items not on the NACDG series; lipstick and cosmetics were the predominant sources. Conclusions: Patch testing is valuable in the evaluation and identification of contact allergy in patients referred for lip dermatitis. The use of supplementary allergens based on history and exposure is important in the identification of additional relevant allergens. Over a third of patients with contact allergy had other factors, such as irritant dermatitis, considered relevant to their condition.

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