Optimal low-density lipoprotein is 50 to 70 mg/dl: Lower is better and physiologically normal

James H. O'Keefe, Loren Cordain, William Harris, Richard M. Moe, Robert Vogel

Research output: Contribution to journalArticle

352 Citations (Scopus)

Abstract

The normal low-density lipoprotein (LDL) cholesterol range is 50 to 70 mg/dl for native hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals (all of whom do not develop atherosclerosis). Randomized trial data suggest atherosclerosis progression and coronary heart disease events are minimized when LDL is lowered to

Original languageEnglish (US)
Pages (from-to)2142-2146
Number of pages5
JournalJournal of the American College of Cardiology
Volume43
Issue number11
DOIs
StatePublished - Jun 2 2004
Externally publishedYes

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LDL Lipoproteins
Atherosclerosis
LDL Cholesterol
Primates
Coronary Disease
Mammals

Keywords

  • CHD
  • coronary heart disease
  • LDL
  • low density lipoprotein
  • Natural Cholesterol Education Program-Adult Treatment Panel-III
  • NCEP-ATP-III

ASJC Scopus subject areas

  • Nursing(all)

Cite this

Optimal low-density lipoprotein is 50 to 70 mg/dl : Lower is better and physiologically normal. / O'Keefe, James H.; Cordain, Loren; Harris, William; Moe, Richard M.; Vogel, Robert.

In: Journal of the American College of Cardiology, Vol. 43, No. 11, 02.06.2004, p. 2142-2146.

Research output: Contribution to journalArticle

O'Keefe, James H. ; Cordain, Loren ; Harris, William ; Moe, Richard M. ; Vogel, Robert. / Optimal low-density lipoprotein is 50 to 70 mg/dl : Lower is better and physiologically normal. In: Journal of the American College of Cardiology. 2004 ; Vol. 43, No. 11. pp. 2142-2146.
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