Optimal low-density lipoprotein is 50 to 70 mg/dl: Lower is better and physiologically normal

James H. O'Keefe, Loren Cordain, William Harris, Richard M. Moe, Robert Vogel

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The normal low-density lipoprotein (LDL) cholesterol range is 50 to 70 mg/dl for native hunter-gatherers, healthy human neonates, free-living primates, and other wild mammals (all of whom do not develop atherosclerosis). Randomized trial data suggest atherosclerosis progression and coronary heart disease events are minimized when LDL is lowered to

Original languageEnglish (US)
Pages (from-to)2142-2146
Number of pages5
JournalJournal of the American College of Cardiology
Issue number11
Publication statusPublished - Jun 2 2004
Externally publishedYes



  • CHD
  • coronary heart disease
  • LDL
  • low density lipoprotein
  • Natural Cholesterol Education Program-Adult Treatment Panel-III

ASJC Scopus subject areas

  • Nursing(all)

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