Optical Coherence Tomography Assessment of Angle Anatomy Changes After Cataract Surgery

Farnaz Memarzadeh; Maolong Tang; Yan Li; Vikas Chopra; Brian A. Francis; David Huang

doi:10.1016/j.ajo.2007.04.009

Optical Coherence Tomography Assessment of Angle Anatomy Changes After Cataract Surgery

Farnaz Memarzadeh, Maolong Tang, Yan Li, Vikas Chopra, Brian A. Francis, David Huang

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Purpose: To evaluate changes in anterior chamber (AC) morphology induced by cataract extraction using anterior segment optical coherence tomography (OCT). Design: Prospective comparative observational case series. Methods: Thirty-two eyes of 32 patients underwent OCT imaging of the angle before and after cataract surgery. Anterior chamber depth (ACD), angle opening distance at 500 μm (AOD₅₀₀) and trabecular-iris space at 500 μm (TISA₅₀₀) were measured pre- and postoperatively. Preoperative lens thickness (LT) and lens position (LP) were calculated. Results: ACD, AOD₅₀₀, and TISA₅₀₀ increased significantly after cataract extraction (P < .001). Preoperatively, ACD and LT highly correlated (P = .0083) as did ACD and TISA₅₀₀ (P = .0001). TISA₅₀₀ correlated with LP (P = .0001) but not with LT (P = .74). Conclusions: Changes in angle morphology after cataract surgery can be imaged and objectively quantified by anterior segment OCT. Lens position may have a greater influence on angle width than LT.

Original language	English (US)
Pages (from-to)	464-465
Number of pages	2
Journal	American journal of ophthalmology
Volume	144
Issue number	3
DOIs	https://doi.org/10.1016/j.ajo.2007.04.009
State	Published - Sep 2007
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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@article{3aeaccf7b2a14b0cb05706eade81f4a4,

title = "Optical Coherence Tomography Assessment of Angle Anatomy Changes After Cataract Surgery",

abstract = "Purpose: To evaluate changes in anterior chamber (AC) morphology induced by cataract extraction using anterior segment optical coherence tomography (OCT). Design: Prospective comparative observational case series. Methods: Thirty-two eyes of 32 patients underwent OCT imaging of the angle before and after cataract surgery. Anterior chamber depth (ACD), angle opening distance at 500 μm (AOD500) and trabecular-iris space at 500 μm (TISA500) were measured pre- and postoperatively. Preoperative lens thickness (LT) and lens position (LP) were calculated. Results: ACD, AOD500, and TISA500 increased significantly after cataract extraction (P < .001). Preoperatively, ACD and LT highly correlated (P = .0083) as did ACD and TISA500 (P = .0001). TISA500 correlated with LP (P = .0001) but not with LT (P = .74). Conclusions: Changes in angle morphology after cataract surgery can be imaged and objectively quantified by anterior segment OCT. Lens position may have a greater influence on angle width than LT.",

author = "Farnaz Memarzadeh and Maolong Tang and Yan Li and Vikas Chopra and Francis, {Brian A.} and David Huang",

note = "Funding Information: This study was supported by Grant NIH R01 EY 13516, National Eye Institute, Bethesda, Maryland and an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York. Research equipment and grant support from Carl Zeiss Meditec, Inc, Dublin, California. Dr Huang receives royalties from OCT patents licensed to Carl Zeiss Meditec, Inc. Drs Huang, Tang, and Li received research grant support from Carl Zeiss Meditec, Inc. The authors indicate no financial conflict of interest. Involved in design and conduct of study (D.H., M.T., Y.L.); collection, management, analysis and interpretation of the data (F.M., M.T., Y.L., V.C., B.A.F., D.H.); and preparation, review and approval of the manuscript (F.M., V.C., B.A.F., D.H.). This study was approved by Institutional Review Board of University of Southern California and was conducted in accord with Health Insurance Portability and Accountability Act (HIPAA) regulations.",

year = "2007",

month = sep,

doi = "10.1016/j.ajo.2007.04.009",

language = "English (US)",

volume = "144",

pages = "464--465",

journal = "American Journal of Ophthalmology",

issn = "0002-9394",

publisher = "Elsevier USA",

number = "3",

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TY - JOUR

T1 - Optical Coherence Tomography Assessment of Angle Anatomy Changes After Cataract Surgery

AU - Memarzadeh, Farnaz

AU - Tang, Maolong

AU - Li, Yan

AU - Chopra, Vikas

AU - Francis, Brian A.

AU - Huang, David

N1 - Funding Information: This study was supported by Grant NIH R01 EY 13516, National Eye Institute, Bethesda, Maryland and an unrestricted grant from Research to Prevent Blindness, Inc, New York, New York. Research equipment and grant support from Carl Zeiss Meditec, Inc, Dublin, California. Dr Huang receives royalties from OCT patents licensed to Carl Zeiss Meditec, Inc. Drs Huang, Tang, and Li received research grant support from Carl Zeiss Meditec, Inc. The authors indicate no financial conflict of interest. Involved in design and conduct of study (D.H., M.T., Y.L.); collection, management, analysis and interpretation of the data (F.M., M.T., Y.L., V.C., B.A.F., D.H.); and preparation, review and approval of the manuscript (F.M., V.C., B.A.F., D.H.). This study was approved by Institutional Review Board of University of Southern California and was conducted in accord with Health Insurance Portability and Accountability Act (HIPAA) regulations.

PY - 2007/9

Y1 - 2007/9

N2 - Purpose: To evaluate changes in anterior chamber (AC) morphology induced by cataract extraction using anterior segment optical coherence tomography (OCT). Design: Prospective comparative observational case series. Methods: Thirty-two eyes of 32 patients underwent OCT imaging of the angle before and after cataract surgery. Anterior chamber depth (ACD), angle opening distance at 500 μm (AOD500) and trabecular-iris space at 500 μm (TISA500) were measured pre- and postoperatively. Preoperative lens thickness (LT) and lens position (LP) were calculated. Results: ACD, AOD500, and TISA500 increased significantly after cataract extraction (P < .001). Preoperatively, ACD and LT highly correlated (P = .0083) as did ACD and TISA500 (P = .0001). TISA500 correlated with LP (P = .0001) but not with LT (P = .74). Conclusions: Changes in angle morphology after cataract surgery can be imaged and objectively quantified by anterior segment OCT. Lens position may have a greater influence on angle width than LT.

AB - Purpose: To evaluate changes in anterior chamber (AC) morphology induced by cataract extraction using anterior segment optical coherence tomography (OCT). Design: Prospective comparative observational case series. Methods: Thirty-two eyes of 32 patients underwent OCT imaging of the angle before and after cataract surgery. Anterior chamber depth (ACD), angle opening distance at 500 μm (AOD500) and trabecular-iris space at 500 μm (TISA500) were measured pre- and postoperatively. Preoperative lens thickness (LT) and lens position (LP) were calculated. Results: ACD, AOD500, and TISA500 increased significantly after cataract extraction (P < .001). Preoperatively, ACD and LT highly correlated (P = .0083) as did ACD and TISA500 (P = .0001). TISA500 correlated with LP (P = .0001) but not with LT (P = .74). Conclusions: Changes in angle morphology after cataract surgery can be imaged and objectively quantified by anterior segment OCT. Lens position may have a greater influence on angle width than LT.

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DO - 10.1016/j.ajo.2007.04.009

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JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

SN - 0002-9394

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ER -

Optical Coherence Tomography Assessment of Angle Anatomy Changes After Cataract Surgery

Abstract

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