Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience

Angelena Crown, Elizabeth Carlson, Flavio G. Rocha, Janie W. Grumley

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Intraoperative radiation therapy (IORT) has been shown to reduce local recurrence rates among women with early-stage invasive ductal carcinoma, but data regarding its use among women with in situ carcinoma are limited. In this single-institution study, 50 women with in situ carcinoma were treated with oncoplastic breast-conserving surgery (OPS) and single-dose IORT. All 50 patients had “no tumor on ink,” but 9 (16%) had margins < 2 mm and required additional therapy. No local recurrences were observed after a median follow-up of 46 months. Single-dose IORT is an efficacious treatment for well-selected patients with DCIS.

Original languageEnglish (US)
Pages (from-to)2391-2394
Number of pages4
JournalBreast Journal
Volume26
Issue number12
DOIs
StatePublished - Dec 2020
Externally publishedYes

Keywords

  • ductal Carcinoma in situ
  • early Stage Breast cancer
  • intraoperative radiation therapy

ASJC Scopus subject areas

  • Internal Medicine
  • Surgery
  • Oncology

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