Ocular manifestations of Marek's disease

T. W. Smith, Daniel Albert, N. Robinson, B. W. Calnek, O. Schwabe

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

An experimental study of the ocular changes occurring in Marek's disease was carried out. Marek's disease which is induced by a DNA virus, is a disorder that occurs in chickens and related fowl. Ocular involvement is a feature of this disease. In this study the eye changes of Marek's disease were sequentially examined in specific, pathogen free birds injected with clone purified Marek's disease virus. An infiltration of malignant appearing lymphoreticular proliferative cells was seen initially in the optic nerves, ciliary nerves, and uvea in birds receiving the virus either intraocularly or systemically. Subsequent infiltration of similar cells occurred throughout the eye.

Original languageEnglish (US)
Pages (from-to)586-592
Number of pages7
JournalInvestigative Ophthalmology
Volume13
Issue number8
StatePublished - Dec 1 1974
Externally publishedYes

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Eye Manifestations
Marek Disease
Birds
Uvea
Viruses
Specific Pathogen-Free Organisms
DNA Viruses
Optic Nerve
Chickens
Clone Cells

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Smith, T. W., Albert, D., Robinson, N., Calnek, B. W., & Schwabe, O. (1974). Ocular manifestations of Marek's disease. Investigative Ophthalmology, 13(8), 586-592.

Ocular manifestations of Marek's disease. / Smith, T. W.; Albert, Daniel; Robinson, N.; Calnek, B. W.; Schwabe, O.

In: Investigative Ophthalmology, Vol. 13, No. 8, 01.12.1974, p. 586-592.

Research output: Contribution to journalArticle

Smith, TW, Albert, D, Robinson, N, Calnek, BW & Schwabe, O 1974, 'Ocular manifestations of Marek's disease', Investigative Ophthalmology, vol. 13, no. 8, pp. 586-592.
Smith TW, Albert D, Robinson N, Calnek BW, Schwabe O. Ocular manifestations of Marek's disease. Investigative Ophthalmology. 1974 Dec 1;13(8):586-592.
Smith, T. W. ; Albert, Daniel ; Robinson, N. ; Calnek, B. W. ; Schwabe, O. / Ocular manifestations of Marek's disease. In: Investigative Ophthalmology. 1974 ; Vol. 13, No. 8. pp. 586-592.
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