@article{6acde1f7e4ae49e9b46e16314afa5bee,
title = "Ocular clinical findings and basement membrane changes in Goodpasture's syndrome",
abstract = "Goodpasture's syndrome is a rapidly progressive disease characterized by the onset of pulmonary hemorrhage with glomerulonephritis, leading to pulmonary and renal failure. The hallmark of this disease is linear deposition of antibasement membrane IgG in the basement membranes of the kidney and lung. In two cases of nonrhegmatogenous retinal detachment in patients with Goodpasture's syndrome, the first patient demonstrated multiple ischemic areas in the choroid on fluorescein angiography. Histopathologic and immunologic studies of the eyes of the second patient demonstrated macular edema and elevation of the retina in association with choroidal infarction and linear deposition of IgG in Bruch's membrane and the basement membranes of the choroidal vessels.",
author = "Jampol, {Lee M.} and Moshe Lahav and Albert, {Daniel M.} and Joseph Craft",
note = "Funding Information: Case 1—This 24-year-old white woman was in good health until February 1970, when she had a flu-like illness during pregnancy characterized by myalgias, fever, and cough. In August 1970, she was admitted to a local hospital with shortness of breath, hemoptysis, hematuria, and anemia. Progressive renal failure developed and she was transferred to the Yale-New Haven Hospital where the diagnosis of Goodpasture's syndrome was made. The patient was treated with systemic prednisone and hemodial- From the Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, Connecticut. This study was supported in part by the Ida and Louis Katz Memorial Fund through a grant from Fight for Sight, Inc., New York City, The Seeing Eye, Inc., Morristown, New Jersey, and grant EY-01392-01 from the National Institutes of Health. Reprint requests to Lee M. Jampol, M.D., Illinois Eye and Ear Infirmary, 185S W. Taylor St., Chicago, IL 60612.",
year = "1975",
month = mar,
doi = "10.1016/0002-9394(75)90622-4",
language = "English (US)",
volume = "79",
pages = "452--455",
journal = "American journal of ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "3",
}