Objective measurement of lower extremity function and quality of life after surgical revascularization for critical lower extremity ischemia

Gregory Landry, Nick O. Esmonde, Jason R. Lewis, Amir Azarbal, Timothy Liem, Erica Mitchell, Gregory (Greg) Moneta

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background Outcomes of revascularization for critical limb ischemia (CLI) have historically been patency, limb salvage, and survival. Functional status and quality of life have not been well described. This study used functional and quality of life assessments to measure patient-centered outcomes after revascularization for CLI. Methods The study observed 18 patients (age, 65 ± 11 years) prospectively before and after lower extremity bypass for CLI. Patients completed the Short Physical Performance Battery, which measures walking speed, leg strength, and balance, as well as performed a 6-minute walk, and calorie expenditure was measured by an accelerometer. Isometric muscle strength was assessed with the Muscle Function Evaluation chair (Metitur, Helsinki, Finland). Quality of life instruments included the 36-Item Short Form Health Survey and the Vascular Quality of Life questionnaire. Patients' preoperative status was compared with 4-month postoperative status. Results Muscle Function Evaluation chair measurements of ipsilateral leg strength demonstrated a significant increase in knee flexion from 64 ± 62 N to 135 ± 133 N (P =.038) and nearly significant increase in knee extension from 120 ± 110 N to 186 ± 85 N (P =.062) and ankle plantar flexion from 178 ± 126 N to 267 ± 252 N (P =.078). In the contralateral leg, knee flexion increased from 71 ± 96 N to 149 ± 162 N (P =.028) and knee extension from 162 ± 112 N to 239 ± 158 N (P =.036). Absolute improvements were noted in 6-minute walk distance, daily calorie expenditure, and individual domains and overall Short Physical Performance Battery scores, and upper extremity strength decreased, although none were significant. The Vascular Quality of Life questionnaire captured significant improvement in all individual domains and overall score (P

Original languageEnglish (US)
Pages (from-to)136-142
Number of pages7
JournalJournal of Vascular Surgery
Volume60
Issue number1
DOIs
StatePublished - 2014

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Lower Extremity
Ischemia
Quality of Life
Knee
Leg
Extremities
Health Expenditures
Blood Vessels
Muscles
Limb Salvage
Muscle Strength
Finland
Health Surveys
Ankle
Upper Extremity
Survival
Surveys and Questionnaires

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

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title = "Objective measurement of lower extremity function and quality of life after surgical revascularization for critical lower extremity ischemia",
abstract = "Background Outcomes of revascularization for critical limb ischemia (CLI) have historically been patency, limb salvage, and survival. Functional status and quality of life have not been well described. This study used functional and quality of life assessments to measure patient-centered outcomes after revascularization for CLI. Methods The study observed 18 patients (age, 65 ± 11 years) prospectively before and after lower extremity bypass for CLI. Patients completed the Short Physical Performance Battery, which measures walking speed, leg strength, and balance, as well as performed a 6-minute walk, and calorie expenditure was measured by an accelerometer. Isometric muscle strength was assessed with the Muscle Function Evaluation chair (Metitur, Helsinki, Finland). Quality of life instruments included the 36-Item Short Form Health Survey and the Vascular Quality of Life questionnaire. Patients' preoperative status was compared with 4-month postoperative status. Results Muscle Function Evaluation chair measurements of ipsilateral leg strength demonstrated a significant increase in knee flexion from 64 ± 62 N to 135 ± 133 N (P =.038) and nearly significant increase in knee extension from 120 ± 110 N to 186 ± 85 N (P =.062) and ankle plantar flexion from 178 ± 126 N to 267 ± 252 N (P =.078). In the contralateral leg, knee flexion increased from 71 ± 96 N to 149 ± 162 N (P =.028) and knee extension from 162 ± 112 N to 239 ± 158 N (P =.036). Absolute improvements were noted in 6-minute walk distance, daily calorie expenditure, and individual domains and overall Short Physical Performance Battery scores, and upper extremity strength decreased, although none were significant. The Vascular Quality of Life questionnaire captured significant improvement in all individual domains and overall score (P",
author = "Gregory Landry and Esmonde, {Nick O.} and Lewis, {Jason R.} and Amir Azarbal and Timothy Liem and Erica Mitchell and Moneta, {Gregory (Greg)}",
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T1 - Objective measurement of lower extremity function and quality of life after surgical revascularization for critical lower extremity ischemia

AU - Landry, Gregory

AU - Esmonde, Nick O.

AU - Lewis, Jason R.

AU - Azarbal, Amir

AU - Liem, Timothy

AU - Mitchell, Erica

AU - Moneta, Gregory (Greg)

PY - 2014

Y1 - 2014

N2 - Background Outcomes of revascularization for critical limb ischemia (CLI) have historically been patency, limb salvage, and survival. Functional status and quality of life have not been well described. This study used functional and quality of life assessments to measure patient-centered outcomes after revascularization for CLI. Methods The study observed 18 patients (age, 65 ± 11 years) prospectively before and after lower extremity bypass for CLI. Patients completed the Short Physical Performance Battery, which measures walking speed, leg strength, and balance, as well as performed a 6-minute walk, and calorie expenditure was measured by an accelerometer. Isometric muscle strength was assessed with the Muscle Function Evaluation chair (Metitur, Helsinki, Finland). Quality of life instruments included the 36-Item Short Form Health Survey and the Vascular Quality of Life questionnaire. Patients' preoperative status was compared with 4-month postoperative status. Results Muscle Function Evaluation chair measurements of ipsilateral leg strength demonstrated a significant increase in knee flexion from 64 ± 62 N to 135 ± 133 N (P =.038) and nearly significant increase in knee extension from 120 ± 110 N to 186 ± 85 N (P =.062) and ankle plantar flexion from 178 ± 126 N to 267 ± 252 N (P =.078). In the contralateral leg, knee flexion increased from 71 ± 96 N to 149 ± 162 N (P =.028) and knee extension from 162 ± 112 N to 239 ± 158 N (P =.036). Absolute improvements were noted in 6-minute walk distance, daily calorie expenditure, and individual domains and overall Short Physical Performance Battery scores, and upper extremity strength decreased, although none were significant. The Vascular Quality of Life questionnaire captured significant improvement in all individual domains and overall score (P

AB - Background Outcomes of revascularization for critical limb ischemia (CLI) have historically been patency, limb salvage, and survival. Functional status and quality of life have not been well described. This study used functional and quality of life assessments to measure patient-centered outcomes after revascularization for CLI. Methods The study observed 18 patients (age, 65 ± 11 years) prospectively before and after lower extremity bypass for CLI. Patients completed the Short Physical Performance Battery, which measures walking speed, leg strength, and balance, as well as performed a 6-minute walk, and calorie expenditure was measured by an accelerometer. Isometric muscle strength was assessed with the Muscle Function Evaluation chair (Metitur, Helsinki, Finland). Quality of life instruments included the 36-Item Short Form Health Survey and the Vascular Quality of Life questionnaire. Patients' preoperative status was compared with 4-month postoperative status. Results Muscle Function Evaluation chair measurements of ipsilateral leg strength demonstrated a significant increase in knee flexion from 64 ± 62 N to 135 ± 133 N (P =.038) and nearly significant increase in knee extension from 120 ± 110 N to 186 ± 85 N (P =.062) and ankle plantar flexion from 178 ± 126 N to 267 ± 252 N (P =.078). In the contralateral leg, knee flexion increased from 71 ± 96 N to 149 ± 162 N (P =.028) and knee extension from 162 ± 112 N to 239 ± 158 N (P =.036). Absolute improvements were noted in 6-minute walk distance, daily calorie expenditure, and individual domains and overall Short Physical Performance Battery scores, and upper extremity strength decreased, although none were significant. The Vascular Quality of Life questionnaire captured significant improvement in all individual domains and overall score (P

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