Abstract
Salivary gland tumors can rarely present in skin excision specimens and can pose a diagnostic challenge to dermatopathologists. We present an exceptional case of a salivary gland type nonsebaceous lymphadenoma presenting as a painless subcutaneous nodule on the right medial eyebrow of a 16-year-old male, mimicking a primary cutaneous adnexal neoplasm. Histologic evaluation revealed a well-circumscribed to partially encapsulated nodule with a marked lymphoid infiltrate including reactive germinal centers. Within the lymphoid component was a central epithelial cystic neoplasm with tubuloglandular and basaloid differentiation. There was no myoepithelial component to suggest a chondroid syringoma. No sebaceous differentiation was present. The overall histopathological and immunohistochemical findings were consistent with a nonsebaceous lymphadenoma. Dermatopathologists should consider salivary gland type lymphadenoma as a differential diagnosis when encountering a subcutaneous lesion with lymphoid, cystic, glandular, and basaloid components.
Original language | English (US) |
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Pages (from-to) | 934-937 |
Number of pages | 4 |
Journal | Journal of cutaneous pathology |
Volume | 49 |
Issue number | 11 |
DOIs | |
State | Published - Nov 2022 |
Keywords
- lymphadenoma
- salivary gland tumor
- salivary gland type lymphadenoma
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology
- Dermatology