Noncompliance with arthritis drugs: magnitude, correlates, and clinical implications

R. A. Deyo, T. S. Inui, B. Sullivan

Research output: Contribution to journalArticle

62 Scopus citations


Objective information on arthritis drug compliance in usual care settings is sparse. Of 'causes' of poor compliance, regimen complexity has received special attention. We used a previously validated pharmacy-based compliance measure to study compliance in an arthritis clinic. Across drugs, mean compliance was low (64%). Wide variations were seen among drugs, ranging from 55% mean compliance (indomethacin) to over 80% (prednisone, penicillamine). Major variations by diagnosis were also found, with rheumatoid arthritis patients more compliant than others. Regimen complexity was a relatively weak correlate of compliance, and the overall level of arthritis drug compliance was similar to that reported for antihypertensive drugs.

Original languageEnglish (US)
Pages (from-to)931-936
Number of pages6
JournalJournal of Rheumatology
Issue number6
StatePublished - Dec 1 1981

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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