Non-invasive assessment of the pyramidal tract and motor pathway of primates

A. C. Ludolph, J. Hugon, Peter Spencer

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Non-invasive direct stimulation of the motor cortex of cynomolgus monkeys has been used to assess in awake and anesthetized animals the central and peripheral conduction times of the motor pathway and to measure the latencies of the descending spinal volley of the pyramidal tracts. Repetitive stimulation failed to induce convulsive activity or detectable pathological changes. Peripheral latencies were comparable with those obtained from F-wave analysis. Central conduction times for corticospinal tracts regulating the upper and lower limbs were 2.7 msec and 5.4 msec, respectively, the estimated conduction velocity (67.5 m/sec) corresponding to results obtained by invasive methods. These studies provide a new and apparently safe technique to assess non-invasively the functional status of the central motor pathway in primates, a method that might also find utility in clinical practice.

Original languageEnglish (US)
Pages (from-to)63-67
Number of pages5
JournalElectroencephalography and Clinical Neurophysiology
Volume67
Issue number1
DOIs
StatePublished - 1987
Externally publishedYes

Fingerprint

Efferent Pathways
Pyramidal Tracts
Primates
Macaca fascicularis
Motor Cortex
Lower Extremity

Keywords

  • Motor cortex stimulation
  • Primate
  • Pyramidal tract

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Non-invasive assessment of the pyramidal tract and motor pathway of primates. / Ludolph, A. C.; Hugon, J.; Spencer, Peter.

In: Electroencephalography and Clinical Neurophysiology, Vol. 67, No. 1, 1987, p. 63-67.

Research output: Contribution to journalArticle

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