New Vistas in the Biology of the Flagellum—Leishmania Parasites

Research output: Contribution to journalReview articlepeer-review

Abstract

Like other kinetoplastid protozoa, the flagellum in Leishmania parasites plays central roles throughout the life cycle. Discoveries over the past decade have begun to elucidate flagellar functions at the molecular level in both the insect vector stage promastigotes and intra-macrophage amastigotes. This focused review will highlight recent advances that contribute to understanding flagellar function in the various biological contexts encountered by Leishmania parasites.

Original languageEnglish (US)
Article number447
JournalPathogens
Volume11
Issue number4
DOIs
StatePublished - Apr 2022

Keywords

  • flagellar membrane proteins
  • flagellum
  • flagellum attachment zone
  • protein composition and function
  • protein targeting to flagellum

ASJC Scopus subject areas

  • Immunology and Allergy
  • Molecular Biology
  • Immunology and Microbiology(all)
  • Microbiology (medical)
  • Infectious Diseases

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