Neuroimmunophilin ligands in the treatment of Parkinson's disease

Bruce G. Gold, John G. Nutt

Research output: Contribution to journalReview articlepeer-review

49 Scopus citations

Abstract

Parkinson's disease treatment can be divided into three categories: symptomatic, protective and restorative. This review focuses on the restorative and neuroprotective actions of a new class of potential therapeutic agents, neuroimmunophilin ligands. To date, however, short-term treatments with two such compounds in a non-human primate model and in patients with Parkinson's disease have been disappointing.

Original languageEnglish (US)
Pages (from-to)82-86
Number of pages5
JournalCurrent Opinion in Pharmacology
Volume2
Issue number1
DOIs
StatePublished - Feb 1 2002

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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