Neuroendocrine tumors: Beyond the abdomen

Melissa A. Jacobs, Stefanie Weinstein, Thomas A. Hope, Rizwan Aslam, Judy Yee, Fergus Coakley

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Several classification systems for neuroendocrine tumors (NETs) exist, which use variable terminology and criteria for grading and staging. This variability in terminology can cause confusion and difficulty in recognizing which tumors are, in fact, members of this heterogeneous group of malignancies. The largest group of NETs, the gastroenteropancreatic NETs, has been well described and characterized; however, there are less-recognized extra-abdominal NETs that can arise from nearly any organ in the body. In this article, the clinical features and imaging appearances of the extra-abdominal NETs will be reviewed, compared, and contrasted. This diverse group consists of paragangliomas, Merkel cell carcinomas, esthesioneuroblastomas, NETs of the lung, and medullary thyroid carcinomas. Recognition of these tumors as part of the larger group of NETs is important for understanding how best to approach imaging for their diagnosis, staging, and potential treatment. Familiarity with the computed tomographic and magnetic resonance imaging appearances and the role of radionuclide imaging of these heterogeneous groups aids in the correct diagnosis and in treatment planning.

Original languageEnglish (US)
Pages (from-to)898-914
Number of pages17
JournalJournal of Computer Assisted Tomography
Volume38
Issue number6
StatePublished - Dec 11 2014

Fingerprint

Neuroendocrine Tumors
Abdomen
Terminology
Olfactory Esthesioneuroblastoma
Merkel Cell Carcinoma
Paraganglioma
Confusion
Neoplasms
Radionuclide Imaging
Magnetic Resonance Imaging
Lung

Keywords

  • BIRADS classification
  • Breast carcinoma
  • Lesion descriptors
  • magnetic resonance imaging
  • Scoring system
  • Specificity

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Jacobs, M. A., Weinstein, S., Hope, T. A., Aslam, R., Yee, J., & Coakley, F. (2014). Neuroendocrine tumors: Beyond the abdomen. Journal of Computer Assisted Tomography, 38(6), 898-914.

Neuroendocrine tumors : Beyond the abdomen. / Jacobs, Melissa A.; Weinstein, Stefanie; Hope, Thomas A.; Aslam, Rizwan; Yee, Judy; Coakley, Fergus.

In: Journal of Computer Assisted Tomography, Vol. 38, No. 6, 11.12.2014, p. 898-914.

Research output: Contribution to journalArticle

Jacobs, MA, Weinstein, S, Hope, TA, Aslam, R, Yee, J & Coakley, F 2014, 'Neuroendocrine tumors: Beyond the abdomen', Journal of Computer Assisted Tomography, vol. 38, no. 6, pp. 898-914.
Jacobs MA, Weinstein S, Hope TA, Aslam R, Yee J, Coakley F. Neuroendocrine tumors: Beyond the abdomen. Journal of Computer Assisted Tomography. 2014 Dec 11;38(6):898-914.
Jacobs, Melissa A. ; Weinstein, Stefanie ; Hope, Thomas A. ; Aslam, Rizwan ; Yee, Judy ; Coakley, Fergus. / Neuroendocrine tumors : Beyond the abdomen. In: Journal of Computer Assisted Tomography. 2014 ; Vol. 38, No. 6. pp. 898-914.
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