Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma

J. L. Bennett, Steven L. Galetta, L. P. Frohman, Z. Mourelatos, Sakir Gultekin, J. O. Dalmau, J. B. Posner

Research output: Contribution to journalArticle

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Abstract

The authors report two patients with testicular cancer who exhibited supranuclear gaze disorders as a manifestation of a paraneo-plastic brainstem encephalomyelitis. In the first patient, neuro-ophthalmic dysfunction was accompanied by a prominent limbic encephalitis whereas in the second patient, an unusual, mixed pendular and jerk nystagmus was manifested. Neuroimaging revealed an enhancing hypothalamic mass in the first patient and was negative in the second. Blood from both patients contained an antibody previously reported in a patient with limbic encephalitis and testicular cancer.

Original languageEnglish (US)
Pages (from-to)864-867
Number of pages4
JournalNeurology
Volume52
Issue number4
StatePublished - Mar 10 1999
Externally publishedYes

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Paraneoplastic Syndromes
Carcinoma
Limbic Encephalitis
Pathologic Nystagmus
Testicular Neoplasms
Encephalomyelitis
Neuroimaging
Plastics
Brain Stem
Antibodies

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Bennett, J. L., Galetta, S. L., Frohman, L. P., Mourelatos, Z., Gultekin, S., Dalmau, J. O., & Posner, J. B. (1999). Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma. Neurology, 52(4), 864-867.

Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma. / Bennett, J. L.; Galetta, Steven L.; Frohman, L. P.; Mourelatos, Z.; Gultekin, Sakir; Dalmau, J. O.; Posner, J. B.

In: Neurology, Vol. 52, No. 4, 10.03.1999, p. 864-867.

Research output: Contribution to journalArticle

Bennett, JL, Galetta, SL, Frohman, LP, Mourelatos, Z, Gultekin, S, Dalmau, JO & Posner, JB 1999, 'Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma', Neurology, vol. 52, no. 4, pp. 864-867.
Bennett JL, Galetta SL, Frohman LP, Mourelatos Z, Gultekin S, Dalmau JO et al. Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma. Neurology. 1999 Mar 10;52(4):864-867.
Bennett, J. L. ; Galetta, Steven L. ; Frohman, L. P. ; Mourelatos, Z. ; Gultekin, Sakir ; Dalmau, J. O. ; Posner, J. B. / Neuro-ophthalmologic manifestations of a paraneoplastic syndrome and testicular carcinoma. In: Neurology. 1999 ; Vol. 52, No. 4. pp. 864-867.
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