Nanoscale topographic instabilities of a phospholipid monolayer

W. R. Schief, L. Touryan, Stephen (Steve) Hall, V. Vogel

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Light scattering microscopy reveals previously undetected topographic instabilities in phospholipid monolayers at the air/water interface far below the collapse pressure. Following compression through the fluid - condensed phase transition in monolayers of dipalmitoyl phosphatidylcholine, after the disappearance of the fluid phase, the contact regions between condensed domains acquire static roughness as indicated by enhanced light scattering. With further compression, a nanoscale budding process occurs within the roughened regions, while the interiors of the condensed domains remain flat and retain their domain shapes. At monolayer collapse, the buds proliferate across the entire interface, suggesting that the buds detected at lower pressures represent spatially confined fluctuations into the collapse phase. The confinement of static roughness formation,and budding to domain contact regions indicates that these topographic instabilities originate from packing defects created where adjacent domain edges with conflicting molecular orientations grow together during the fluid - condensed phase transition.

Original languageEnglish (US)
Pages (from-to)7388-7393
Number of pages6
JournalJournal of Physical Chemistry B
Volume104
Issue number31
StatePublished - Aug 10 2000

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Phospholipids
Monolayers
Light scattering
Fluids
Surface roughness
Phase transitions
1,2-Dipalmitoylphosphatidylcholine
Molecular orientation
fluids
light scattering
roughness
Contacts (fluid mechanics)
Microscopic examination
Compaction
Defects
Water
Air
low pressure
microscopy
air

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Engineering(all)

Cite this

Schief, W. R., Touryan, L., Hall, S. S., & Vogel, V. (2000). Nanoscale topographic instabilities of a phospholipid monolayer. Journal of Physical Chemistry B, 104(31), 7388-7393.

Nanoscale topographic instabilities of a phospholipid monolayer. / Schief, W. R.; Touryan, L.; Hall, Stephen (Steve); Vogel, V.

In: Journal of Physical Chemistry B, Vol. 104, No. 31, 10.08.2000, p. 7388-7393.

Research output: Contribution to journalArticle

Schief, WR, Touryan, L, Hall, SS & Vogel, V 2000, 'Nanoscale topographic instabilities of a phospholipid monolayer', Journal of Physical Chemistry B, vol. 104, no. 31, pp. 7388-7393.
Schief, W. R. ; Touryan, L. ; Hall, Stephen (Steve) ; Vogel, V. / Nanoscale topographic instabilities of a phospholipid monolayer. In: Journal of Physical Chemistry B. 2000 ; Vol. 104, No. 31. pp. 7388-7393.
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