TY - JOUR
T1 - Myostatin and insulin-like growth factors in uremic sarcopenia
T2 - The yin and yang in muscle mass regulation
AU - Mak, R. H.
AU - Rotwein, P.
PY - 2006/8/21
Y1 - 2006/8/21
N2 - Myostatin and the insulin-like growth factors (IGF-I and -II) play inhibitory and stimulatory roles, respectively, in the development and regulation of skeletal muscle mass. The findings of Sun et al. in this issue shed light on the potential regulation and actions of this yin-and-yang system in uremic sarcopenia and the salutary effects of exercise.
AB - Myostatin and the insulin-like growth factors (IGF-I and -II) play inhibitory and stimulatory roles, respectively, in the development and regulation of skeletal muscle mass. The findings of Sun et al. in this issue shed light on the potential regulation and actions of this yin-and-yang system in uremic sarcopenia and the salutary effects of exercise.
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U2 - 10.1038/sj.ki.5001622
DO - 10.1038/sj.ki.5001622
M3 - Comment/debate
C2 - 16871252
AN - SCOPUS:33746500122
SN - 0085-2538
VL - 70
SP - 410
EP - 412
JO - Kidney International
JF - Kidney International
IS - 3
ER -