Abstract
When the membrane potential was manually clamped, the non-cholinergic excitatory potential was associated with either a sustained increase, an initial decrease followed by a prolonged increase or no apparent change in neuronal input resistance. In the majority of neurons studied, the amplitude of non-cholinergic depolarization was augmented upon conditioning hyperpolarization, whereas it was attenuated in a low Na solution. The results are consistent with the suggestion that the non-cholinergic depolarization may be generated by a change of multiple conductances that may include GNa activation and GK inactivation.
Original language | English (US) |
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Pages (from-to) | 203-208 |
Number of pages | 6 |
Journal | Brain research |
Volume | 229 |
Issue number | 1 |
DOIs | |
State | Published - Dec 14 1981 |
Externally published | Yes |
Keywords
- G activation
- G inactivation
- non-cholinergic excitatory potential
- sympathetic neurons
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology