Moyamoya syndrome associated with alagille syndrome: Outcome after surgical revascularization

Lissa C. Baird, Edward R. Smith, Rebecca Ichord, David A. Piccoli, Timothy J. Bernard, Nancy B. Spinner, R. Michael Scott, Binita M. Kamath

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Vasculopathy is well-described in Alagille syndrome (ALGS); however, few data exist regarding neurosurgical interventions. We report 5 children with ALGS with moyamoya who underwent revascularization surgery. Postsurgical complications included 1 stroke and 1 death from thalamic hemorrhage. Global function improved in survivors. Revascularization is reasonably safe in patients with ALGS and may improve neurologic outcomes.

Original languageEnglish (US)
Pages (from-to)470-473
Number of pages4
JournalJournal of Pediatrics
Volume166
Issue number2
DOIs
StatePublished - Feb 1 2015

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Baird, L. C., Smith, E. R., Ichord, R., Piccoli, D. A., Bernard, T. J., Spinner, N. B., Scott, R. M., & Kamath, B. M. (2015). Moyamoya syndrome associated with alagille syndrome: Outcome after surgical revascularization. Journal of Pediatrics, 166(2), 470-473. https://doi.org/10.1016/j.jpeds.2014.10.067