Mortality and survival in Alzheimer's disease: A 15-year community study

Mary Ganguli, Hiroko Dodge

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

Alzheimer's disease (AD) is considered a leading cause of death but few studies have examined the contribution of AD to mortality based on followup of representative cohorts. In a fifteen-year prospective epidemiological study of 1670 adults aged 65+ years a rural US community, we found that AD was responsible for 4.9% of deaths in this elderly cohort. AD increased the risk of mortality by 40% in the cohort as a whole and in women but not in men. Mean (SD) duration of survival with AD was 5.9 (3.7) years, and longer with earlier age at onset. Death certificates of AD subjects were significantly more likely to list dementia/AD, other brain disorders, pneumonia, and dehydration; and significantly less likely to include cancer.

Original languageEnglish (US)
Title of host publicationResearch and Practice in Alzheimer's Disease
Pages277-283
Number of pages7
Volume11
StatePublished - 2006
Externally publishedYes

Publication series

NameResearch and Practice in Alzheimer's Disease
Volume11
ISSN (Print)12848360

Fingerprint

Alzheimer Disease
Survival
Mortality
Death Certificates
Brain Diseases
Rural Population
Alzheimer Disease 15
Dehydration
Age of Onset
Dementia
Epidemiologic Studies
Cause of Death
Pneumonia
Prospective Studies
Neoplasms

Keywords

  • Alzheimer's
  • Dementia
  • Epidemiology
  • Mortality risk
  • Population attributable risk (PAR)

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Neuropsychology and Physiological Psychology

Cite this

Ganguli, M., & Dodge, H. (2006). Mortality and survival in Alzheimer's disease: A 15-year community study. In Research and Practice in Alzheimer's Disease (Vol. 11, pp. 277-283). (Research and Practice in Alzheimer's Disease; Vol. 11).

Mortality and survival in Alzheimer's disease : A 15-year community study. / Ganguli, Mary; Dodge, Hiroko.

Research and Practice in Alzheimer's Disease. Vol. 11 2006. p. 277-283 (Research and Practice in Alzheimer's Disease; Vol. 11).

Research output: Chapter in Book/Report/Conference proceedingChapter

Ganguli, M & Dodge, H 2006, Mortality and survival in Alzheimer's disease: A 15-year community study. in Research and Practice in Alzheimer's Disease. vol. 11, Research and Practice in Alzheimer's Disease, vol. 11, pp. 277-283.
Ganguli M, Dodge H. Mortality and survival in Alzheimer's disease: A 15-year community study. In Research and Practice in Alzheimer's Disease. Vol. 11. 2006. p. 277-283. (Research and Practice in Alzheimer's Disease).
Ganguli, Mary ; Dodge, Hiroko. / Mortality and survival in Alzheimer's disease : A 15-year community study. Research and Practice in Alzheimer's Disease. Vol. 11 2006. pp. 277-283 (Research and Practice in Alzheimer's Disease).
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