Molecular screening for breast cancer prevention, early detection, and treatment planning

Combining biomarkers from DNA, RNA, and protein

Katherine Stemke-Hale, Bryan Hennessy, Gordon Mills, Rahul Mitra

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

The completion of the human genome project, along with the ancillary technologies derived from this effort, provides the ability to comprehensively analyze patient tumors as well as the individual patient's own genetic make-up at the DNA, RNA, and protein level. As a result, novel molecular screening techniques have the potential to push the boundaries of detection to even smaller tumors and also to allow accurate risk assessment, cancer prevention, and treatment planning in individual women. This review focuses on advances over the past 2 years in the use of molecular signatures and circulating tumor cells for early breast cancer detection and for prediction of response to therapy.

Original languageEnglish (US)
Pages (from-to)484-491
Number of pages8
JournalCurrent Oncology Reports
Volume8
Issue number6
DOIs
StatePublished - Nov 1 2006
Externally publishedYes

Fingerprint

Biomarkers
RNA
Breast Neoplasms
DNA
Human Genome Project
Circulating Neoplastic Cells
Neoplasms
Proteins
Early Detection of Cancer
Therapeutics
Technology

ASJC Scopus subject areas

  • Oncology

Cite this

Molecular screening for breast cancer prevention, early detection, and treatment planning : Combining biomarkers from DNA, RNA, and protein. / Stemke-Hale, Katherine; Hennessy, Bryan; Mills, Gordon; Mitra, Rahul.

In: Current Oncology Reports, Vol. 8, No. 6, 01.11.2006, p. 484-491.

Research output: Contribution to journalReview article

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