Molecular screening for breast cancer prevention, early detection, and treatment planning: Combining biomarkers from DNA, RNA, and protein

Katherine Stemke-Hale, Bryan Hennessy, Gordon B. Mills, Rahul Mitra

    Research output: Contribution to journalReview article

    6 Scopus citations

    Abstract

    The completion of the human genome project, along with the ancillary technologies derived from this effort, provides the ability to comprehensively analyze patient tumors as well as the individual patient's own genetic make-up at the DNA, RNA, and protein level. As a result, novel molecular screening techniques have the potential to push the boundaries of detection to even smaller tumors and also to allow accurate risk assessment, cancer prevention, and treatment planning in individual women. This review focuses on advances over the past 2 years in the use of molecular signatures and circulating tumor cells for early breast cancer detection and for prediction of response to therapy.

    Original languageEnglish (US)
    Pages (from-to)484-491
    Number of pages8
    JournalCurrent oncology reports
    Volume8
    Issue number6
    DOIs
    StatePublished - Nov 1 2006

    ASJC Scopus subject areas

    • Oncology

    Fingerprint Dive into the research topics of 'Molecular screening for breast cancer prevention, early detection, and treatment planning: Combining biomarkers from DNA, RNA, and protein'. Together they form a unique fingerprint.

  • Cite this