Molecular machinery of auditory and vestibular transduction

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na+ channel family.

Original languageEnglish (US)
Pages (from-to)449-455
Number of pages7
JournalCurrent Opinion in Neurobiology
Volume5
Issue number4
DOIs
StatePublished - 1995
Externally publishedYes

Fingerprint

Myosin Type I
Amiloride
Myosins

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Molecular machinery of auditory and vestibular transduction. / Barr-Gillespie, Peter.

In: Current Opinion in Neurobiology, Vol. 5, No. 4, 1995, p. 449-455.

Research output: Contribution to journalArticle

@article{e44287ef5b634476841764c973f227b6,
title = "Molecular machinery of auditory and vestibular transduction",
abstract = "The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na+ channel family.",
author = "Peter Barr-Gillespie",
year = "1995",
doi = "10.1016/0959-4388(95)80004-2",
language = "English (US)",
volume = "5",
pages = "449--455",
journal = "Current Opinion in Neurobiology",
issn = "0959-4388",
publisher = "Elsevier Limited",
number = "4",

}

TY - JOUR

T1 - Molecular machinery of auditory and vestibular transduction

AU - Barr-Gillespie, Peter

PY - 1995

Y1 - 1995

N2 - The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na+ channel family.

AB - The hunt for molecules that conduct mechanoelectrical transduction in hair cells has recently intensified. A hair cell's transduction apparatus adapts to sustained stimuli, and myosin Iβ and myosin VIIA have been advanced as candidates for the motor that mediates this process. The identity of the transduction channel remains unknown, although a viable suggestion proposes that it belongs to the amiloride-sensitive Na+ channel family.

UR - http://www.scopus.com/inward/record.url?scp=0029091128&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029091128&partnerID=8YFLogxK

U2 - 10.1016/0959-4388(95)80004-2

DO - 10.1016/0959-4388(95)80004-2

M3 - Article

C2 - 7488845

AN - SCOPUS:0029091128

VL - 5

SP - 449

EP - 455

JO - Current Opinion in Neurobiology

JF - Current Opinion in Neurobiology

SN - 0959-4388

IS - 4

ER -