MOLEKULARGENETISCHER NACHWEIS EINER POLYKLONALEN IMMUNANTWORT BEI AUTOIMMUNTHYREOIDITIS UND ENTZUNDLICHEN DARMERKRANKUNGEN

Translated title of the contribution: Molecular genetic detection of a polyclonal immune response in autoimmune thyroid disease and inflammatory bowel disease

W. Kaulfersch, J. R. Baker, K. D. Burman, C. Fiocchi, A. J. Ahmann, J. C. D'Avis, T. A. Waldmann

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Southern blot hybridization techniques were used to analyze the arrangements of the immunoglobulin and the T cell antigen receptor genes in lymphocytes of patients with Graves disease and Hashimoto's thyroiditis as well as in patients with Crohn's disease, chronic ulcerative colitis, and with other gastrointestinal disease. The results indicate that the immune response of autoimmune thyroid disease and inflammatory bowel disease is of polyclonal origin.

Translated title of the contributionMolecular genetic detection of a polyclonal immune response in autoimmune thyroid disease and inflammatory bowel disease
Original languageGerman
Pages (from-to)610-615
Number of pages6
JournalMonatsschrift fur Kinderheilkunde
Volume137
Issue number9
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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  • Cite this

    Kaulfersch, W., Baker, J. R., Burman, K. D., Fiocchi, C., Ahmann, A. J., D'Avis, J. C., & Waldmann, T. A. (1989). MOLEKULARGENETISCHER NACHWEIS EINER POLYKLONALEN IMMUNANTWORT BEI AUTOIMMUNTHYREOIDITIS UND ENTZUNDLICHEN DARMERKRANKUNGEN. Monatsschrift fur Kinderheilkunde, 137(9), 610-615.