Molecular diagnosis: Implications for ophthalmology

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

The effort to subdivide diseases and to individualize therapies based on characteristics of the patient has been labeled precision medicine. Jameson and Longo define precision medicine as "treatments targeted to the needs of individual patients on the basis of genetic, biomarker, phenotypic or psychosocial characteristics that distinguish a given patient from other patients with similar clinical presentations" (Jameson and Longo, 2015). We illustrate how molecular diagnosis can be applied to orbital inflammatory disease to achieve the goals of precision medicine.

Original languageEnglish (US)
Pages (from-to)25-33
Number of pages9
JournalProgress in Retinal and Eye Research
Volume50
DOIs
StatePublished - Jan 1 2016

Keywords

  • Granulomatosis with polyangiitis
  • Molecular diagnosis
  • Nonspecific orbital inflammatory disease
  • Sarcoidosis
  • Thyroid eye disease
  • Transcriptomics

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

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