TY - JOUR
T1 - Models of Caries Formation around Dental Composite Restorations
AU - Ferracane, J. L.
N1 - Funding Information:
A portion of this work was supported by a grant from the National Institutes of Health/National Institute of Dental and Craniofacial Research (RO1 DE021372).
Publisher Copyright:
© International & American Associations for Dental Research.
PY - 2017/4/1
Y1 - 2017/4/1
N2 - The main reason cited for the replacement of dental composite restorations is the recurrence of caries. Numerous models - both in vitro, with acid gels or bacterial biofilms, and in situ, with dental appliances - have been used to study caries formation around dental composites. The literature shows that many factors may affect caries formation, including marginal gap formation, gap size, the local chemical environment, the durability of the bonded interface, the extent of bacterial penetration, and the presence of mechanical loading. Studies have also shown that what have been called wall lesions may form independent of surface lesions, though not likely due to microleakage through very small gap spaces in the clinical situation. Gap size and mechanical loading have been shown to be related to lesion severity within in vitro models, but these results do not correspond exactly with those obtained from in situ studies using restorations in dental appliances. Though not conclusive, some in vitro models have shown that certain materials possessing antimicrobial characteristics may reduce the severity of lesion formation, suggesting possible pathways for developing new composite and adhesive materials for restorations with potentially enhanced longevity.
AB - The main reason cited for the replacement of dental composite restorations is the recurrence of caries. Numerous models - both in vitro, with acid gels or bacterial biofilms, and in situ, with dental appliances - have been used to study caries formation around dental composites. The literature shows that many factors may affect caries formation, including marginal gap formation, gap size, the local chemical environment, the durability of the bonded interface, the extent of bacterial penetration, and the presence of mechanical loading. Studies have also shown that what have been called wall lesions may form independent of surface lesions, though not likely due to microleakage through very small gap spaces in the clinical situation. Gap size and mechanical loading have been shown to be related to lesion severity within in vitro models, but these results do not correspond exactly with those obtained from in situ studies using restorations in dental appliances. Though not conclusive, some in vitro models have shown that certain materials possessing antimicrobial characteristics may reduce the severity of lesion formation, suggesting possible pathways for developing new composite and adhesive materials for restorations with potentially enhanced longevity.
KW - antimicrobial agents
KW - composite resins
KW - dental caries
KW - dental leakage
KW - dental restorations
KW - mechanical stress
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U2 - 10.1177/0022034516683395
DO - 10.1177/0022034516683395
M3 - Review article
C2 - 28318391
AN - SCOPUS:85016128841
SN - 0022-0345
VL - 96
SP - 364
EP - 371
JO - Journal of Dental Research
JF - Journal of Dental Research
IS - 4
ER -