Mind the Gap: Putting Evidence into Practice in the Era of Learning Health Systems

Jeanne Marie Guise, Lucy A. Savitz, Charles P. Friedman

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations


Due to the increasing amount of available published evidence and the continual need to apply and update evidence in practice, we propose a shift in the way evidence generated by learning health systems can be integrated into more traditional evidence reviews. This paper discusses two main mechanisms to close the evidence-to-practice gap: (1) integrating Learning Health System (LHS) results with existing systematic review evidence and (2) providing this combined evidence in a standardized, computable data format. We believe these efforts will better inform practice, thereby improving individual and population health.

Original languageEnglish (US)
Pages (from-to)2237-2239
Number of pages3
JournalJournal of general internal medicine
Issue number12
StatePublished - Dec 1 2018
Externally publishedYes


  • evidence-based medicine
  • health care delivery
  • health information technology
  • implementation research
  • systematic reviews

ASJC Scopus subject areas

  • Internal Medicine


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