Abstract
Adult-onset Still's disease (AOSD) is a multi-system inflammatory disorder characterized by high spiking fevers, evanescent salmon-coloured rash, arthralgias or arthritis, hepatosplenomegaly, lymphadenopathy and sore throat. There is no specific test or combination of tests that can establish the diagnosis of AOSD and patients may present with other systemic involvement including neurological manifestations in 7-12% of cases. We present a complex case of a patient with AOSD who developed the Miller-Fisher variant of Guillain-Barré syndrome. This immunological disorder of the nervous system has not been described in association with AOSD before. We also review the literature on other neurological manifestations in AOSD. AOSD mimics different disease processes and its multi-system manifestations may complicate the picture further.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 216-222 |
| Number of pages | 7 |
| Journal | Rheumatology |
| Volume | 41 |
| Issue number | 2 |
| State | Published - 2002 |
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Keywords
- Adult Still's disease
- Gangliosides
- Guillain-Barré syndrome
- Miller Fisher syndrome
- Neurological manifestations
- Still's disease
ASJC Scopus subject areas
- Neuroscience(all)
- Rheumatology
Cite this
Miller Fisher syndrome in adult onset Still's disease : Case report and review of the literature of other neurological manifestations. / Desai, Sima; Allen, Elizabeth; Deodhar, Atulya (Atul).
In: Rheumatology, Vol. 41, No. 2, 2002, p. 216-222.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Miller Fisher syndrome in adult onset Still's disease
T2 - Case report and review of the literature of other neurological manifestations
AU - Desai, Sima
AU - Allen, Elizabeth
AU - Deodhar, Atulya (Atul)
PY - 2002
Y1 - 2002
N2 - Adult-onset Still's disease (AOSD) is a multi-system inflammatory disorder characterized by high spiking fevers, evanescent salmon-coloured rash, arthralgias or arthritis, hepatosplenomegaly, lymphadenopathy and sore throat. There is no specific test or combination of tests that can establish the diagnosis of AOSD and patients may present with other systemic involvement including neurological manifestations in 7-12% of cases. We present a complex case of a patient with AOSD who developed the Miller-Fisher variant of Guillain-Barré syndrome. This immunological disorder of the nervous system has not been described in association with AOSD before. We also review the literature on other neurological manifestations in AOSD. AOSD mimics different disease processes and its multi-system manifestations may complicate the picture further.
AB - Adult-onset Still's disease (AOSD) is a multi-system inflammatory disorder characterized by high spiking fevers, evanescent salmon-coloured rash, arthralgias or arthritis, hepatosplenomegaly, lymphadenopathy and sore throat. There is no specific test or combination of tests that can establish the diagnosis of AOSD and patients may present with other systemic involvement including neurological manifestations in 7-12% of cases. We present a complex case of a patient with AOSD who developed the Miller-Fisher variant of Guillain-Barré syndrome. This immunological disorder of the nervous system has not been described in association with AOSD before. We also review the literature on other neurological manifestations in AOSD. AOSD mimics different disease processes and its multi-system manifestations may complicate the picture further.
KW - Adult Still's disease
KW - Gangliosides
KW - Guillain-Barré syndrome
KW - Miller Fisher syndrome
KW - Neurological manifestations
KW - Still's disease
UR - http://www.scopus.com/inward/record.url?scp=0036108901&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036108901&partnerID=8YFLogxK
M3 - Article
C2 - 11886973
AN - SCOPUS:0036108901
VL - 41
SP - 216
EP - 222
JO - Rheumatology (United Kingdom)
JF - Rheumatology (United Kingdom)
SN - 1462-0324
IS - 2
ER -