Microbiology of orbital cellulitis with subperiosteal abscess in children: Prevalence and characteristics of Streptococcus anginosus group infection

Caroline N. Vloka, Donna H. Kim, John D. Ng

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To evaluate the predominant pathogens and clinical course in pediatric patients with orbital cellulitis (OC) complicated by subperiosteal abscess (SPA). Methods: This is a single-center retrospective chart review evaluating pediatric patients with OC complicated by SPA treated at a tertiary care center in the Pacific Northwest. Data were analyzed for characteristics, rates of infection, and antibiotic resistance of the predominant pathogens in pediatric patients. Results: Twenty-seven children were identified with OC complicated by SPA and bacterial cultures drawn. The average age (SD) of the patients was 9.2 years (4.8), median 9.6; 15 range 5 months to 17.2 years. Seventeen (63.0%) were male. Sinusitis was present in all patients. Streptococcus species were the most common pathogen accounting for 52% (17/33) of isolates. Streptococcus anginosus group (SAG) was the predominant species and were isolated in 10 out of 27 (37%) children in the study. Twenty-one (78%) patients required surgery for the treatment of SPA. Among surgically treated patients, females tended to be younger than males (p =.068). Pediatric patients with SAG infections required more surgery than children without this isolate, 100% and 65%, respectively (p =.030). Female patients tended to have SAG infections more often than males (p =.063). Conclusions: Orbital infections caused by SAG require surgical management more often than those caused by other pathogens. Our results suggest a difference in pathogenic organisms in male and female patients with SPA. SAG is one of the most common pathogens isolated in orbital cellulitis complicated by SPA in children.

Original languageEnglish (US)
JournalOrbit (London)
DOIs
StateAccepted/In press - 2021

Keywords

  • Microbiology
  • Streptococcus anginosus
  • orbital cellulitis
  • subperiosteal abscess

ASJC Scopus subject areas

  • Ophthalmology

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