Abstract
Objective: We evaluated whether metabolic syndrome (MetS) is associated with an increased incidence of lower extremity peripheral artery disease (PAD) in community dwelling people free of clinical cardiovascular disease at baseline. We assessed whether higher levels of inflammatory biomarkers may mediate the association of MetS with incident PAD. Methods: MetS was defined at baseline as the presence of three or more of the following components: elevated waist circumference, triglycerides ≥150 mg/dL, reduced high-density lipoprotein (HDL) cholesterol, blood pressure ≥130/85 mm Hg or taking blood pressure medication, and fasting glucose ≥100 mg/dL and
| Original language | English (US) |
|---|---|
| Pages (from-to) | 198-203 |
| Number of pages | 6 |
| Journal | Atherosclerosis |
| Volume | 243 |
| Issue number | 1 |
| DOIs | |
| State | Published - Nov 1 2015 |
Fingerprint
Keywords
- Cardiovascular disease
- Metabolic syndrome
- Peripheral artery disease
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
Cite this
Metabolic syndrome and incident peripheral artery disease - The Multi-Ethnic Study of Atherosclerosis. / Vidula, Himabindu; Liu, Kiang; Criqui, Michael H.; Szklo, Moyses; Allison, Matthew; Sibley, Christopher; Ouyang, Pamela; Tracy, Russell P.; Chan, Cheeling; McDermott, Mary M.
In: Atherosclerosis, Vol. 243, No. 1, 01.11.2015, p. 198-203.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Metabolic syndrome and incident peripheral artery disease - The Multi-Ethnic Study of Atherosclerosis
AU - Vidula, Himabindu
AU - Liu, Kiang
AU - Criqui, Michael H.
AU - Szklo, Moyses
AU - Allison, Matthew
AU - Sibley, Christopher
AU - Ouyang, Pamela
AU - Tracy, Russell P.
AU - Chan, Cheeling
AU - McDermott, Mary M.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Objective: We evaluated whether metabolic syndrome (MetS) is associated with an increased incidence of lower extremity peripheral artery disease (PAD) in community dwelling people free of clinical cardiovascular disease at baseline. We assessed whether higher levels of inflammatory biomarkers may mediate the association of MetS with incident PAD. Methods: MetS was defined at baseline as the presence of three or more of the following components: elevated waist circumference, triglycerides ≥150 mg/dL, reduced high-density lipoprotein (HDL) cholesterol, blood pressure ≥130/85 mm Hg or taking blood pressure medication, and fasting glucose ≥100 mg/dL and
AB - Objective: We evaluated whether metabolic syndrome (MetS) is associated with an increased incidence of lower extremity peripheral artery disease (PAD) in community dwelling people free of clinical cardiovascular disease at baseline. We assessed whether higher levels of inflammatory biomarkers may mediate the association of MetS with incident PAD. Methods: MetS was defined at baseline as the presence of three or more of the following components: elevated waist circumference, triglycerides ≥150 mg/dL, reduced high-density lipoprotein (HDL) cholesterol, blood pressure ≥130/85 mm Hg or taking blood pressure medication, and fasting glucose ≥100 mg/dL and
KW - Cardiovascular disease
KW - Metabolic syndrome
KW - Peripheral artery disease
UR - http://www.scopus.com/inward/record.url?scp=84942112938&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84942112938&partnerID=8YFLogxK
U2 - 10.1016/j.atherosclerosis.2015.08.044
DO - 10.1016/j.atherosclerosis.2015.08.044
M3 - Article
C2 - 26398292
AN - SCOPUS:84942112938
VL - 243
SP - 198
EP - 203
JO - Atherosclerosis
JF - Atherosclerosis
SN - 0021-9150
IS - 1
ER -