Measuring quality of life in children with obstructive sleep disorders

Lianne M. De Serres, Craig Derkay, Susan Astley, Richard (Rick) Deyo, Richard M. Rosenfeld, George A. Gates

Research output: Contribution to journalArticle

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Abstract

Objective: To validate a disease-specific health-related quality of life (HRQOL) instrument for children with obstructive sleep disorders (OSDs). Design: Prospective cohort study using a 6-item health-related instrument (OSD-6). Subjects: One hundred caregivers of patients with OSDs secondary to adenotonsillar hypertrophy (age range, 2-12 years) from 2 tertiary care, pediatric otolaryngology practices. Intervention: The OSD-6 was administered on initial presentation and 4 to 5 weeks after adenotonsillectomy. A subset of patients repeated the OSD-6 within 3 weeks after presentation to assess test-retest reliability. Main Outcome Measures: Test-retest reliability, internal consistency, construct validity, and responsiveness to clinical change of the OSD-6 score. Results: Test-retest reliability was good (intraclass correlation coefficient = 0.74). Median OSD-6 score was 4.5 (0- to 6-point scale) with higher scores indicating poorer quality of life (QOL). Construct validity was demonstrated by the moderate correlation between OSD-6 score and global adenoid and tonsil-related QOL (R = -0.62), strong correlation between the OSD-6 change score and change in global adenoid and tonsil-related QOL (R = -0.63), and the moderate correlation between the change score and parent estimate of clinical change (R = 0.40). The mean change in OSD-6 score after adenotonsillectomy was 3.0 (95% confidence interval, 2.7-3.4). The mean standardized response was 2.3 (95% confidence interval, 1.9-2.7) indicating the instrument's large responsiveness to clinical change. The change score was very reliable (R = 0.85). Conclusions: The OSD-6 is a reliable, responsive, easily administered instrument. It is valid for detecting change after adenotonsillectomy in children with OSDs.

Original languageEnglish (US)
Pages (from-to)1423-1429
Number of pages7
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume126
Issue number12
StatePublished - 2000
Externally publishedYes

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Quality of Life
Reproducibility of Results
Adenoids
Palatine Tonsil
Sleep Wake Disorders
Confidence Intervals
Otolaryngology
Tertiary Healthcare
Hypertrophy
Caregivers
Cohort Studies
Outcome Assessment (Health Care)
Prospective Studies
Pediatrics
Health

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

De Serres, L. M., Derkay, C., Astley, S., Deyo, R. R., Rosenfeld, R. M., & Gates, G. A. (2000). Measuring quality of life in children with obstructive sleep disorders. Archives of Otolaryngology - Head and Neck Surgery, 126(12), 1423-1429.

Measuring quality of life in children with obstructive sleep disorders. / De Serres, Lianne M.; Derkay, Craig; Astley, Susan; Deyo, Richard (Rick); Rosenfeld, Richard M.; Gates, George A.

In: Archives of Otolaryngology - Head and Neck Surgery, Vol. 126, No. 12, 2000, p. 1423-1429.

Research output: Contribution to journalArticle

De Serres, LM, Derkay, C, Astley, S, Deyo, RR, Rosenfeld, RM & Gates, GA 2000, 'Measuring quality of life in children with obstructive sleep disorders', Archives of Otolaryngology - Head and Neck Surgery, vol. 126, no. 12, pp. 1423-1429.
De Serres, Lianne M. ; Derkay, Craig ; Astley, Susan ; Deyo, Richard (Rick) ; Rosenfeld, Richard M. ; Gates, George A. / Measuring quality of life in children with obstructive sleep disorders. In: Archives of Otolaryngology - Head and Neck Surgery. 2000 ; Vol. 126, No. 12. pp. 1423-1429.
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