Maternal plasma and amniotic fluid dehydroepiandrosterone-sulfate concentrations in preterm labor and delivery

M. Mazor, F. Ghezzi, J. Cohen, R. Hershkovitz, Jorge Tolosa, J. Levy, J. R. Leiberman, M. Glezerman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The purpose of this study was to determine whether preterm parturition is associated with changes in maternal plasma and amniotic fluid dehydroepiandrosterone-sulfate concentrations. A cross sectional study was constructed according to the gestational age at admission and response to tocolysis. Group 1 consisted of women admitted with preterm labor and intact membranes between 28 and 31 weeks and 6 days gestational age (n=40). Group 2 included 40 patients with preterm labor between 32 and 36 weeks gestational age. Both groups were classified into two subgroups: preterm delivery within seven days of admission and term delivery. Commercially available immunoassay kits validated for amniotic fluid analysis of DHEA-S, were used to measure maternal plasma and amniotic fluid DHEA-S concentrations. Maternal plasma DHEA-S concentrations were significantly higher in women with preterm labor who delivered preterm than in those who delivered at term. (Group 1: median 800 ng/ml [range 100-1100] vs. median 200 ng/ml [70-800], P

Original languageEnglish (US)
Pages (from-to)7-12
Number of pages6
JournalArchives of Gynecology and Obstetrics
Volume259
Issue number1
DOIs
StatePublished - Sep 1996
Externally publishedYes

Fingerprint

Dehydroepiandrosterone Sulfate
Dehydroepiandrosterone
Premature Obstetric Labor
Amniotic Fluid
Gestational Age
Mothers
Tocolysis
Immunoassay
Cross-Sectional Studies
Parturition
Membranes

Keywords

  • Amniotic fluid
  • Dehydroepiandrosterone-sulfate
  • Parturition
  • Plasma
  • Preterm labor

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Maternal plasma and amniotic fluid dehydroepiandrosterone-sulfate concentrations in preterm labor and delivery. / Mazor, M.; Ghezzi, F.; Cohen, J.; Hershkovitz, R.; Tolosa, Jorge; Levy, J.; Leiberman, J. R.; Glezerman, M.

In: Archives of Gynecology and Obstetrics, Vol. 259, No. 1, 09.1996, p. 7-12.

Research output: Contribution to journalArticle

Mazor, M. ; Ghezzi, F. ; Cohen, J. ; Hershkovitz, R. ; Tolosa, Jorge ; Levy, J. ; Leiberman, J. R. ; Glezerman, M. / Maternal plasma and amniotic fluid dehydroepiandrosterone-sulfate concentrations in preterm labor and delivery. In: Archives of Gynecology and Obstetrics. 1996 ; Vol. 259, No. 1. pp. 7-12.
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