Management of Autonomic Dysfunction in Parkinson's Disease

Ronald F. Pfeiffer

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


Autonomic dysfunction is a frequent and important nonmotor feature of Parkinson's disease (PD). Autonomic dysfunction in PD spans a broad clinical spectrum. Cardiovascular dysfunction is characterized most prominently by orthostatic hypotension. Gastrointestinal dysfunction can involve virtually all levels of the gastrointestinal tract. Urinary dysfunction can entail either too frequent voiding or difficulty voiding. Sexual dysfunction is frequent and frustrating for both the patient and the partner. Alterations in sweating and body temperature are not widely recognized, but often are present. The presence of effective treatment for at least some aspects of autonomic dysfunction makes it vitally important that the assessment of autonomic dysfunction be a regular component of the neurologic history and examination for individuals with PD.

Original languageEnglish (US)
Pages (from-to)176-185
Number of pages10
JournalSeminars in Neurology
Issue number2
StatePublished - Apr 1 2017


  • autonomic
  • erectile dysfunction
  • gastrointestinal
  • orthostatic hypotension
  • thermoregulatory
  • urinary

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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