Malignancy following treatment of rheumatoid arthritis with cyclophosphamide. Long-term case-control follow-up study

Gary L. Baker, Leslie Kahl, Benny C. Zee, Bertrand L. Stolzer, Amrit K. Agarwal, Thomas A. Medsger

Research output: Contribution to journalArticle

195 Citations (Scopus)

Abstract

A long-term retrospective case-control study was performed comparing 119 patients with rheumatoid arthritis treated with cyclophosphamide and 119 matched control patients with rheumatoid arthritis not treated with cyclophosphamide to determine the risk of subsequent malignancy. Thirty-seven malignancies were detected in 29 cyclophosphamide-treated patients, while 16 malignancies were found in 16 control patients (p

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalThe American journal of medicine
Volume83
Issue number1
DOIs
StatePublished - 1987
Externally publishedYes

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Cyclophosphamide
Rheumatoid Arthritis
Neoplasms
Therapeutics
Case-Control Studies

ASJC Scopus subject areas

  • Nursing(all)

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Malignancy following treatment of rheumatoid arthritis with cyclophosphamide. Long-term case-control follow-up study. / Baker, Gary L.; Kahl, Leslie; Zee, Benny C.; Stolzer, Bertrand L.; Agarwal, Amrit K.; Medsger, Thomas A.

In: The American journal of medicine, Vol. 83, No. 1, 1987, p. 1-9.

Research output: Contribution to journalArticle

Baker, Gary L. ; Kahl, Leslie ; Zee, Benny C. ; Stolzer, Bertrand L. ; Agarwal, Amrit K. ; Medsger, Thomas A. / Malignancy following treatment of rheumatoid arthritis with cyclophosphamide. Long-term case-control follow-up study. In: The American journal of medicine. 1987 ; Vol. 83, No. 1. pp. 1-9.
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