Magnetic susceptibility shift selected imaging: MESSI

Y. Xu, J. A. Balschi, Charles Jr Springer

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Paramagnetic compounds are often used to enhance contrast in MRI by virtue of their increase in the kinetics of the relaxation of water 1H magnetization. Here, we demonstrate a method for contrast enhancement which is based on the resonance frequency shifts caused by the bulk magnetic susceptibility (BMS) effects of such compounds. This involves the frequency selective excitation in the absence of field gradients, during the imaging sequence, of a portion of the water 1H resonance which is rendered inhomogeneous by BMS shifts only. The image which results is of that portion of the sample which gives rise to the portion of the spectrum excited. A phantom sample which simulates some aspects of tissue, particularly blood vessels with different orientations in the magnetic field, was prepared. The contrast enhancement exhibited here avoids some of the distortions attendant to the use of paramagnetic reagents. This new approach can, in principle, utilize the natural BMS differences found in all tissue.

Original languageEnglish (US)
Pages (from-to)80-90
Number of pages11
JournalMagnetic Resonance in Medicine
Volume16
Issue number1
StatePublished - 1990
Externally publishedYes

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Water
Magnetic Fields
Blood Vessels

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Magnetic susceptibility shift selected imaging : MESSI. / Xu, Y.; Balschi, J. A.; Springer, Charles Jr.

In: Magnetic Resonance in Medicine, Vol. 16, No. 1, 1990, p. 80-90.

Research output: Contribution to journalArticle

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