Magnetic nanoparticles in the imaging of tumor angiogenesis

Shaunagh McDermott, Alexander R. Guimaraes

Research output: Contribution to journalReview articlepeer-review

Abstract

Angiogenesis, the growth of new capillary blood vessels, is central to the growth of tumors. Non-invasive imaging of tumor angiogenesis will allow for earlier detection of tumors and also the development of surrogate markers for assessing response to treatment. Steady state magnetic resonance imaging with magnetic nanoparticles is one method to assess angiogenesis. In this article we explain the theory behind steady state magnetic resonance imaging and review the available literature.

Original languageEnglish (US)
Pages (from-to)525-534
Number of pages10
JournalApplied Sciences (Switzerland)
Volume2
Issue number2
DOIs
StatePublished - Jun 1 2012
Externally publishedYes

Keywords

  • Angiogenesis
  • Magnetic resonance imaging
  • Ultrasmall superparamagnetic iron oxide

ASJC Scopus subject areas

  • Materials Science(all)
  • Instrumentation
  • Engineering(all)
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes

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