Macrophages and Metabolism in the Tumor Microenvironment

Ilio Vitale, Gwenola Manic, Lisa M. Coussens, Guido Kroemer, Lorenzo Galluzzi

Research output: Contribution to journalReview articlepeer-review

493 Scopus citations


Vitale et al. discuss the metabolic circuitries whereby tumor-associated macrophages condition their microenvironment to support the cancer growth, metastatic dissemination and resistance to treatment, and how such pathways can be therapeutically targeted.

Original languageEnglish (US)
Pages (from-to)36-50
Number of pages15
JournalCell Metabolism
Issue number1
StatePublished - Jul 2 2019


  • fatty acid oxidation
  • glycolysis
  • hypoxia
  • immunosuppressive metabolites
  • immunotherapy
  • oxidative phosphorylation

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology


Dive into the research topics of 'Macrophages and Metabolism in the Tumor Microenvironment'. Together they form a unique fingerprint.

Cite this