Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements

J. A. Viator, G. Paltauf, Steven Jacques, S. A. Prahl

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Photoacoustic imaging may be used to detect tumor masses in biological tissue. In particular, time of flight measurements of the photoacoustic waves may indicate tumor location. Here we use time of flight information to localize spherical photoacoustic sources in tissue phantoms. A Q-switched, frequency-doubled Nd:YAG laser operating at 532 nm with a pulse duration of 5 ns irradiated absorbing spheres 2 mm in diameter. The spheres were in mineral oil or turbid acrylamide blocks. A PVDF acoustic transducer was built and used to detect the acoustic waves. The position of the detector was translated so that the time of flight information from two acoustic waveforms from the source could be correlated by a convolution algorithm. This convolution resulted in a two dimensional map indicating the position of the source. Source location was indicated to within 5% of the true location for acoustic propagation distances of 20 mm. An image source is also indicated when the true source was in proximity to a reflecting boundary.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages89-99
Number of pages11
Volume3916
StatePublished - 2000
EventBiomedical Optoacoustics - San Jose, CA, USA
Duration: Jan 25 2000Jan 26 2000

Other

OtherBiomedical Optoacoustics
CitySan Jose, CA, USA
Period1/25/001/26/00

Fingerprint

Photoacoustic effect
Light sources
Gels
gels
Convolution
Tumors
Acoustics
Tissue
Acoustic transducers
Mineral oils
convolution integrals
acoustics
Laser pulses
tumors
Acoustic waves
Detectors
Imaging techniques
mineral oils
acoustic propagation
Lasers

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Viator, J. A., Paltauf, G., Jacques, S., & Prahl, S. A. (2000). Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3916, pp. 89-99). Society of Photo-Optical Instrumentation Engineers.

Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements. / Viator, J. A.; Paltauf, G.; Jacques, Steven; Prahl, S. A.

Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3916 Society of Photo-Optical Instrumentation Engineers, 2000. p. 89-99.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Viator, JA, Paltauf, G, Jacques, S & Prahl, SA 2000, Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements. in Proceedings of SPIE - The International Society for Optical Engineering. vol. 3916, Society of Photo-Optical Instrumentation Engineers, pp. 89-99, Biomedical Optoacoustics, San Jose, CA, USA, 1/25/00.
Viator JA, Paltauf G, Jacques S, Prahl SA. Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements. In Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3916. Society of Photo-Optical Instrumentation Engineers. 2000. p. 89-99
Viator, J. A. ; Paltauf, G. ; Jacques, Steven ; Prahl, S. A. / Localization of spherical photoacoustic sources in acrylamide gels using time domain measurements. Proceedings of SPIE - The International Society for Optical Engineering. Vol. 3916 Society of Photo-Optical Instrumentation Engineers, 2000. pp. 89-99
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