Localization and reoperation results for persistent and recurrent parathyroid carcinoma

E. Kebebew, C. Arici, Q. Y. Duh, O. H. Clark, D. Byrd, R. G. Latimer, T. X. O'Connell, W. P. Schecter, John Vetto, J. A. Ryan, J. A. Norton, J. MacFarlane, Clark

Research output: Contribution to journalArticle

141 Citations (Scopus)

Abstract

Hypothesis: Reoperation is safe and benefits patients with persistent and recurrent parathyroid carcinoma. Design: Retrospective study. The mean follow-up time was 8.1 years (median, 7 years; range, 1-23 years). Setting: A university tertiary referral center. Patients: Eighteen patients treated for parathyroid carcinoma from 1966 to 1999. Results: The mean serum calcium level was 13.7 mg/dL (3.43 mmol/L), and the parathyroid hormone (PTH) level was 1.6 to 20 times the upper limit of normal. Fourteen of 18 patients had persistent or recurrent parathyroid carcinoma and underwent 54 reoperations (28 at our institution). Mean time to recurrence was 4.8 years (range, 1-20 years). Symptoms of hyperparathyroidism were relieved in 86% of patients who had reoperation (P

Original languageEnglish (US)
Pages (from-to)878-885
Number of pages8
JournalArchives of Surgery
Volume136
Issue number8
StatePublished - 2001
Externally publishedYes

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Parathyroid Neoplasms
Reoperation
Hyperparathyroidism
Parathyroid Hormone
Tertiary Care Centers
Retrospective Studies
Calcium
Recurrence
Serum

ASJC Scopus subject areas

  • Surgery

Cite this

Kebebew, E., Arici, C., Duh, Q. Y., Clark, O. H., Byrd, D., Latimer, R. G., ... Clark (2001). Localization and reoperation results for persistent and recurrent parathyroid carcinoma. Archives of Surgery, 136(8), 878-885.

Localization and reoperation results for persistent and recurrent parathyroid carcinoma. / Kebebew, E.; Arici, C.; Duh, Q. Y.; Clark, O. H.; Byrd, D.; Latimer, R. G.; O'Connell, T. X.; Schecter, W. P.; Vetto, John; Ryan, J. A.; Norton, J. A.; MacFarlane, J.; Clark.

In: Archives of Surgery, Vol. 136, No. 8, 2001, p. 878-885.

Research output: Contribution to journalArticle

Kebebew, E, Arici, C, Duh, QY, Clark, OH, Byrd, D, Latimer, RG, O'Connell, TX, Schecter, WP, Vetto, J, Ryan, JA, Norton, JA, MacFarlane, J & Clark 2001, 'Localization and reoperation results for persistent and recurrent parathyroid carcinoma', Archives of Surgery, vol. 136, no. 8, pp. 878-885.
Kebebew E, Arici C, Duh QY, Clark OH, Byrd D, Latimer RG et al. Localization and reoperation results for persistent and recurrent parathyroid carcinoma. Archives of Surgery. 2001;136(8):878-885.
Kebebew, E. ; Arici, C. ; Duh, Q. Y. ; Clark, O. H. ; Byrd, D. ; Latimer, R. G. ; O'Connell, T. X. ; Schecter, W. P. ; Vetto, John ; Ryan, J. A. ; Norton, J. A. ; MacFarlane, J. ; Clark. / Localization and reoperation results for persistent and recurrent parathyroid carcinoma. In: Archives of Surgery. 2001 ; Vol. 136, No. 8. pp. 878-885.
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