Lithium: Effects on subjective functioning and morphine-induced euphoria

Donald R. Jasinski; John G. Nutt; Charles A. Haertzen; John D. Griffith; William E. Bunney

doi:10.1126/science.319532

Lithium: Effects on subjective functioning and morphine-induced euphoria

Donald R. Jasinski, John G. Nutt, Charles A. Haertzen, John D. Griffith, William E. Bunney

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The therapeutic usefulness of lithium in decreasing the euphoria and other symptoms associated with manic behavior and the hypothesis of a common final mechanism for elevations in mood have led to speculation that lithium may block the euphoria induced by drugs of abuse. In this study, lithium alone was antieuphoric in drug-free opiate addicts and, further, did not block morphine-indu fed euphoria.

Original language	English (US)
Pages (from-to)	582-584
Number of pages	3
Journal	Science
Volume	195
Issue number	4278
DOIs	https://doi.org/10.1126/science.319532
State	Published - 1977
Externally published	Yes

ASJC Scopus subject areas

General

Access to Document

10.1126/science.319532

Cite this

@article{14cec146be49421090fc1b9364f9912c,

title = "Lithium: Effects on subjective functioning and morphine-induced euphoria",

abstract = "The therapeutic usefulness of lithium in decreasing the euphoria and other symptoms associated with manic behavior and the hypothesis of a common final mechanism for elevations in mood have led to speculation that lithium may block the euphoria induced by drugs of abuse. In this study, lithium alone was antieuphoric in drug-free opiate addicts and, further, did not block morphine-indu fed euphoria.",

author = "Jasinski, {Donald R.} and Nutt, {John G.} and Haertzen, {Charles A.} and Griffith, {John D.} and Bunney, {William E.}",

year = "1977",

doi = "10.1126/science.319532",

language = "English (US)",

volume = "195",

pages = "582--584",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4278",

}

TY - JOUR

T1 - Lithium

T2 - Effects on subjective functioning and morphine-induced euphoria

AU - Jasinski, Donald R.

AU - Nutt, John G.

AU - Haertzen, Charles A.

AU - Griffith, John D.

AU - Bunney, William E.

PY - 1977

Y1 - 1977

N2 - The therapeutic usefulness of lithium in decreasing the euphoria and other symptoms associated with manic behavior and the hypothesis of a common final mechanism for elevations in mood have led to speculation that lithium may block the euphoria induced by drugs of abuse. In this study, lithium alone was antieuphoric in drug-free opiate addicts and, further, did not block morphine-indu fed euphoria.

AB - The therapeutic usefulness of lithium in decreasing the euphoria and other symptoms associated with manic behavior and the hypothesis of a common final mechanism for elevations in mood have led to speculation that lithium may block the euphoria induced by drugs of abuse. In this study, lithium alone was antieuphoric in drug-free opiate addicts and, further, did not block morphine-indu fed euphoria.

UR - http://www.scopus.com/inward/record.url?scp=0017353869&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017353869&partnerID=8YFLogxK

U2 - 10.1126/science.319532

DO - 10.1126/science.319532

M3 - Article

C2 - 319532

AN - SCOPUS:0017353869

SN - 0036-8075

VL - 195

SP - 582

EP - 584

JO - Science

JF - Science

IS - 4278

ER -

Lithium: Effects on subjective functioning and morphine-induced euphoria

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this