Liquid crystals: A novel approach for cancer detection and treatment

Jayalakshmi Vallamkondu, Edwin Bernard Corgiat, Gollapelli Buchaiah, Ramesh Kandimalla, P. Hemachandra Reddy

    Research output: Contribution to journalReview article

    10 Scopus citations

    Abstract

    Liquid crystals are defined as the fourth state of matter forming between solid and liquid states. Earlier the applications of liquid crystals were confined to electronic instruments, but recent research findings suggest multiple applications of liquid crystals in biology and medicine. Here, the purpose of this review article is to discuss the potential biological impacts of liquid crystals in the diagnosis and prognosis of cancer along with the risk assessment. In this review, we also discussed the recent advances of liquid crystals in cancer biomarker detection and treatment in multiple cell line models. Cases reviewed here will demonstrate that cancer diagnostics based on the multidisciplinary technology and intriguingly utilization of liquid crystals may become an alternative to regular cancer detection methodologies. Additionally, we discussed the formidable challenges and problems in applying liquid crystal technologies. Solving these problems will require great effort and the way forward is through the multidisciplinary collaboration of physicists, biologists, chemists, material-scientists, clinicians, and engineers. The triumphant outcome of these liquid crystals and their applications in cancer research would be convenient testing for the detection of cancer and may result in treating the cancer patients non-invasively.

    Original languageEnglish (US)
    Article number462
    JournalCancers
    Volume10
    Issue number11
    DOIs
    StatePublished - Nov 21 2018

    Keywords

    • Antitumor drug
    • Biomarker
    • Biosensor
    • Cancers
    • Liquid crystals

    ASJC Scopus subject areas

    • Oncology
    • Cancer Research

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  • Cite this

    Vallamkondu, J., Corgiat, E. B., Buchaiah, G., Kandimalla, R., & Reddy, P. H. (2018). Liquid crystals: A novel approach for cancer detection and treatment. Cancers, 10(11), [462]. https://doi.org/10.3390/cancers10110462