Linking Delay Discounting and Substance Use Disorders

Genotypes and Phenotypes

Research output: Contribution to journalArticle

Abstract

Research supports the idea that “delay discounting,” also known as temporal discounting, intertemporal choice, or impulsive choice, is a transdisease process with a strong connection to substance use disorders (SUDs) and other psychopathologies, like attention deficit hyperactivity disorder and depression. This article briefly reviews the evidence used to conclude that delay discounting is heritable and should be considered to be an endophenotype, as well as evidence of its behavioral and genetic associations with SUDs. It also discusses the limitations that should be considered when evaluating the strength of these associations. Finally, this article briefly describes research examining relationships among delay discounting and SUD-associated intermediate phenotypes to better understand the conceptual relationships underlying the links between SUDs and delay discounting, and identifies research gaps that should be addressed.

Original languageEnglish (US)
JournalPerspectives on Behavior Science
DOIs
StatePublished - Jan 1 2019

Fingerprint

Substance-Related Disorders
Genotype
Phenotype
Research
Endophenotypes
Behavioral Genetics
Attention Deficit Disorder with Hyperactivity
Psychopathology
Delay Discounting
Depression

Keywords

  • Addiction
  • Alcohol
  • Behavioral genetics
  • Delay discounting
  • Impulsivity
  • Nicotine

ASJC Scopus subject areas

  • Social Psychology
  • Experimental and Cognitive Psychology
  • Clinical Psychology

Cite this

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title = "Linking Delay Discounting and Substance Use Disorders: Genotypes and Phenotypes",
abstract = "Research supports the idea that “delay discounting,” also known as temporal discounting, intertemporal choice, or impulsive choice, is a transdisease process with a strong connection to substance use disorders (SUDs) and other psychopathologies, like attention deficit hyperactivity disorder and depression. This article briefly reviews the evidence used to conclude that delay discounting is heritable and should be considered to be an endophenotype, as well as evidence of its behavioral and genetic associations with SUDs. It also discusses the limitations that should be considered when evaluating the strength of these associations. Finally, this article briefly describes research examining relationships among delay discounting and SUD-associated intermediate phenotypes to better understand the conceptual relationships underlying the links between SUDs and delay discounting, and identifies research gaps that should be addressed.",
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