Ligneous Conjunctivitis With Ear Involvement

Dennis M. Marcus, David Walton, Peter Donshik, Lisa Choo, Richard A. Newman, Daniel Albert

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

We report the association of ligneous conjunctivitis with middle-ear and tympanic membrane involvement in two children. Eye and ear specimens revealed histopathologic and ultrastructural findings consistent with ligneous conjunctivitis, characterized by an amorphous, eosinophilic material with acute and chronic non-granulomatous inflammation. Ear specimens demonstrated granulation tissue along with the above features. Conjunctival and ear lesions from these patients were studied histochemically, immunohistochemically, and ultrastructurally. Our studies demonstrate fibrin and albumin deposition as a common feature in all lesions. Deposition of other components, such as mucopolysaccharides, amyloid, immunoglobulins, and mast cells, were, however, variable. The diversified nature of these lesions, together with the association of eye and ear disease, substantiates the existence of an underlying systemic disorder of unknown cause.

Original languageEnglish (US)
Pages (from-to)514-519
Number of pages6
JournalArchives of ophthalmology
Volume108
Issue number4
DOIs
StatePublished - Jan 1 1990
Externally publishedYes

Fingerprint

Ear
Ear Diseases
Tympanic Membrane
Granulation Tissue
Eye Diseases
Middle Ear
Glycosaminoglycans
Fibrin
Amyloid
Mast Cells
Immunoglobulins
Albumins
Inflammation
Type I Plasminogen Deficiency

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Marcus, D. M., Walton, D., Donshik, P., Choo, L., Newman, R. A., & Albert, D. (1990). Ligneous Conjunctivitis With Ear Involvement. Archives of ophthalmology, 108(4), 514-519. https://doi.org/10.1001/archopht.1990.01070060062050

Ligneous Conjunctivitis With Ear Involvement. / Marcus, Dennis M.; Walton, David; Donshik, Peter; Choo, Lisa; Newman, Richard A.; Albert, Daniel.

In: Archives of ophthalmology, Vol. 108, No. 4, 01.01.1990, p. 514-519.

Research output: Contribution to journalArticle

Marcus, DM, Walton, D, Donshik, P, Choo, L, Newman, RA & Albert, D 1990, 'Ligneous Conjunctivitis With Ear Involvement', Archives of ophthalmology, vol. 108, no. 4, pp. 514-519. https://doi.org/10.1001/archopht.1990.01070060062050
Marcus, Dennis M. ; Walton, David ; Donshik, Peter ; Choo, Lisa ; Newman, Richard A. ; Albert, Daniel. / Ligneous Conjunctivitis With Ear Involvement. In: Archives of ophthalmology. 1990 ; Vol. 108, No. 4. pp. 514-519.
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