Karyotypic analysis of a near diploid established mouse cell line

R. A. Farber, Robert (Mike) Liskay

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A near diploid mouse cell line has been produced from C57BL/6J X AKR/J F1 hybrid embryonic cells by spontaneous transformation. The modal chromosome number of this line is 41 (2n = 40), with low numerical and structural variation relative to other mouse lines which have been reported. Giemsa banded karyotypes on a number of clones and subclones from this line have been analyzed. The most modal karyotypes deviate very little from that of a normal diploid female. Most of the cells have two X chromosomes, one of which is unlabeled early in the S phase.

Original languageEnglish (US)
Pages (from-to)384-396
Number of pages13
JournalCytogenetics and Cell Genetics
Volume13
Issue number4
StatePublished - 1974
Externally publishedYes

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Diploidy
Karyotype
Cell Line
Hybrid Cells
X Chromosome
S Phase
Clone Cells
Chromosomes

ASJC Scopus subject areas

  • Cell Biology
  • Genetics

Cite this

Karyotypic analysis of a near diploid established mouse cell line. / Farber, R. A.; Liskay, Robert (Mike).

In: Cytogenetics and Cell Genetics, Vol. 13, No. 4, 1974, p. 384-396.

Research output: Contribution to journalArticle

Farber, RA & Liskay, RM 1974, 'Karyotypic analysis of a near diploid established mouse cell line', Cytogenetics and Cell Genetics, vol. 13, no. 4, pp. 384-396.
Farber, R. A. ; Liskay, Robert (Mike). / Karyotypic analysis of a near diploid established mouse cell line. In: Cytogenetics and Cell Genetics. 1974 ; Vol. 13, No. 4. pp. 384-396.
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