Intraoperative cell salvage in radical retropubic prostatectomy.

C. L. Gray, Christopher Amling, G. R. Polston, C. R. Powell, C. J. Kane

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

OBJECTIVES: To investigate the efficacy and safety of intraoperative cell salvage with autotransfusion using leukocyte reduction filters in patients undergoing radical retropubic prostatectomy (RRP). METHODS: Between September 1996 and March 1999, 62 patients (age range 48 to 70 years) with clinically localized prostate cancer underwent RRP with intraoperative cell salvage as the sole blood management technique. Salvaged blood was passed through a leukocyte reduction filter before autotransfusion. The 62 cell salvage patients were compared with a cohort who predonated 1 to 3 U autologous blood (n = 101). The estimated blood loss, preoperative and postoperative hematocrit, need for homologous transfusion, and biochemical recurrence rates were compared between the two groups. The progression-free survival rates were compared using the Kaplan-Meier method. RESULTS: No difference was found in preoperative prostate-specific antigen level, pathologic stage, or estimated blood loss between the cell salvage and autologous predonation groups. The preoperative and postoperative hematocrit levels were higher in the cell salvage group (42.7% versus 39.6% and 31.3% versus 27.9%, respectively; P

Original languageEnglish (US)
Pages (from-to)740-745
Number of pages6
JournalUrology
Volume58
Issue number5
StatePublished - Nov 2001
Externally publishedYes

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Prostatectomy
Autologous Blood Transfusions
Hematocrit
Leukocytes
Postoperative Hemorrhage
Prostate-Specific Antigen
Disease-Free Survival
Prostatic Neoplasms
Survival Rate
Safety
Recurrence

ASJC Scopus subject areas

  • Urology

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Gray, C. L., Amling, C., Polston, G. R., Powell, C. R., & Kane, C. J. (2001). Intraoperative cell salvage in radical retropubic prostatectomy. Urology, 58(5), 740-745.

Intraoperative cell salvage in radical retropubic prostatectomy. / Gray, C. L.; Amling, Christopher; Polston, G. R.; Powell, C. R.; Kane, C. J.

In: Urology, Vol. 58, No. 5, 11.2001, p. 740-745.

Research output: Contribution to journalArticle

Gray, CL, Amling, C, Polston, GR, Powell, CR & Kane, CJ 2001, 'Intraoperative cell salvage in radical retropubic prostatectomy.', Urology, vol. 58, no. 5, pp. 740-745.
Gray CL, Amling C, Polston GR, Powell CR, Kane CJ. Intraoperative cell salvage in radical retropubic prostatectomy. Urology. 2001 Nov;58(5):740-745.
Gray, C. L. ; Amling, Christopher ; Polston, G. R. ; Powell, C. R. ; Kane, C. J. / Intraoperative cell salvage in radical retropubic prostatectomy. In: Urology. 2001 ; Vol. 58, No. 5. pp. 740-745.
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